ID A0A453I4K7_AEGTS Unreviewed; 751 AA.
AC A0A453I4K7;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=GTP diphosphokinase {ECO:0000256|ARBA:ARBA00013251};
DE EC=2.7.6.5 {ECO:0000256|ARBA:ARBA00013251};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET4Gv20444400.18, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET4Gv20444400.18}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RelA/SpoT family.
CC {ECO:0000256|ARBA:ARBA00007476}.
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DR AlphaFoldDB; A0A453I4K7; -.
DR EnsemblPlants; AET4Gv20444400.18; AET4Gv20444400.18; AET4Gv20444400.
DR Gramene; AET4Gv20444400.18; AET4Gv20444400.18; AET4Gv20444400.
DR Proteomes; UP000015105; Chromosome 4D.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0008728; F:GTP diphosphokinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0015969; P:guanosine tetraphosphate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR CDD; cd05399; NT_Rel-Spo_like; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR007685; RelA_SpoT.
DR InterPro; IPR004095; TGS.
DR InterPro; IPR012676; TGS-like.
DR PANTHER; PTHR43061; GTP DIPHOSPHOKINASE RSH1, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR43061:SF1; GTP DIPHOSPHOKINASE RSH1, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF13328; HD_4; 1.
DR Pfam; PF04607; RelA_SpoT; 1.
DR Pfam; PF02824; TGS; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00954; RelA_SpoT; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81271; TGS-like; 1.
DR PROSITE; PS51831; HD; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW Stress response {ECO:0000256|ARBA:ARBA00023016};
KW Transferase {ECO:0000256|ARBA:ARBA00022777}.
FT DOMAIN 310..417
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT REGION 30..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 94..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 751 AA; 83173 MW; BFA7C3455B8B771B CRC64;
IHAIPAAKPE KIIRKPQEQN RKEIIGKLKV ESETGRGKAP ASNPALSHRQ PYFTSPRPRP
LCGLRPLLSL LLPRLASSLL LPFGKPPLAL HRSPSSAQFA PCRSPGPRRG PPFAGRRAAD
EIGRRRAMQP PTAALSASSL ECASSCRALW KGGGGAGRPY ECSVLSCAWN APRALTGALA
STTQCSSCSH AEAVGGGRRR GRPRQSNNNT LLHITWAEDI NKGKLGHGSS ASFVSSVKKI
RYWSTPVKSM WRVSCYSSGP FDLVSPETLW ESLRPAISYL QPEELNFVHD ALKLAYEAHN
GQKRRSGEPF IIHPVEVARI LGEHELDWES IAAGLLHDTV EDTDMVTFET IQNEFGATVS
RIVEGETKVS KLGKLQCKNE GSSKQDVKAE DLRQMFLAMT EEVRVIIVKL ADRLHNMRTL
THMPQHKQYA IAMETLQVFA PLAKLLGMYQ IKSELEYLSF MYMNPGDFAE LRKRVDDIFK
AHEQELEEAN KILKQKIAED QFLDLVSVET EVRSVCKELY SIYKTALKSK SSLNEVNQVA
QLRIIIKPKS CNGVGPLCTG QQICYHVLGL VHGIWTPIPQ AVKDYIATPK PNGYQSLHTT
VIPFLNESMF HLEVQIRTED MDLIAERGIA AHYSGRGVVS GPVRPGISSG RNLDGKVICL
NNTGFALRIG WLNAIREWQE EFVGNMSSRE FVDTITRDLL GSRVFVFTPK GEIKNLPKGA
TVIDYAYLIH TEIGNKMVAA KVSCGNISSM I
//
