ID   A0A453I4T5_AEGTS        Unreviewed;      1047 AA.
AC   A0A453I4T5;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   RecName: Full=FANCI solenoid 4 domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Aegilops tauschii subsp. strangulata (Goatgrass).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX   NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET4Gv20443900.11, ECO:0000313|Proteomes:UP000015105};
RN   [1] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=25035499; DOI=10.1126/science.1250092;
RG   International Wheat Genome Sequencing Consortium,;
RA   Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA   Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT   "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL   Science 345:1250092-1250092(2014).
RN   [2] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA   Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA   Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT   "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL   Nat. Plants 3:946-955(2017).
RN   [3] {ECO:0000313|EnsemblPlants:AET4Gv20443900.11}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (MAR-2019) to UniProtKB.
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DR   AlphaFoldDB; A0A453I4T5; -.
DR   EnsemblPlants; AET4Gv20443900.11; AET4Gv20443900.11; AET4Gv20443900.
DR   Gramene; AET4Gv20443900.11; AET4Gv20443900.11; AET4Gv20443900.
DR   Proteomes; UP000015105; Chromosome 4D.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   InterPro; IPR026171; FANCI.
DR   InterPro; IPR029310; FANCI_HD1.
DR   InterPro; IPR029312; FANCI_HD2.
DR   InterPro; IPR029315; FANCI_S2.
DR   InterPro; IPR029314; FANCI_S4.
DR   PANTHER; PTHR21818; BC025462 PROTEIN; 1.
DR   PANTHER; PTHR21818:SF0; FANCONI ANEMIA GROUP I PROTEIN; 1.
DR   Pfam; PF14679; FANCI_HD1; 1.
DR   Pfam; PF14680; FANCI_HD2; 1.
DR   Pfam; PF14676; FANCI_S2; 1.
DR   Pfam; PF14678; FANCI_S4; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000015105}.
FT   DOMAIN          8..88
FT                   /note="FANCI helical"
FT                   /evidence="ECO:0000259|Pfam:PF14679"
FT   DOMAIN          102..230
FT                   /note="FANCI solenoid 2"
FT                   /evidence="ECO:0000259|Pfam:PF14676"
FT   DOMAIN          301..538
FT                   /note="FANCI helical"
FT                   /evidence="ECO:0000259|Pfam:PF14680"
FT   DOMAIN          842..953
FT                   /note="FANCI solenoid 4"
FT                   /evidence="ECO:0000259|Pfam:PF14678"
FT   DOMAIN          978..1042
FT                   /note="FANCI solenoid 4"
FT                   /evidence="ECO:0000259|Pfam:PF14678"
FT   REGION          536..570
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        536..560
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1047 AA;  117382 MW;  FC2A2B246346BB3E CRC64;
     AVKQDPALAR EVVAAVKANA AGVLNGFAVA VLLSVARVRR FNDSAVGVLR DAATTSRRDY
     RMSRRCKWLP DPLKEESVEA AHCVEKALLK AVAESIGGRE HVVPSIVQVG FLLLEASNGD
     PGDEDGPDEG VMSTEEIGVN MLKSLFETHE MARTEIIEQC KFRILSAKPQ QSAPVLRLLG
     CLVRSHPFPM LEYVAHLKEL LDYLPFMNDK ISTGLINCIL PLTKFSRDLK VCDLNSIPCF
     CCCELGYDDC GGINFQDYII LVVRKAMFKR ADAVRIAATN AIVELIVTES EYRKNEANPF
     QDSSSQPSSS QQPEIHREVG VELFQELSGL LRRCLSQQAR VKTVLYEGLI RIVTSDPDVA
     DNVLDFLWPH FLNYYIENAE CPLKMDSCFK VENAKVCMVE PLDCLLSCVS CILRAQQNSK
     CHRPRDAYWK CFGFAPSQDN EVGRSSSRDL FMKGLSNIQK YLRKCLTEDQ RGQTQEAGSA
     SSSLEIVQCH NVFMPGIVEV FVDFAASKLA EAADEPKEKL EKEILELVDA HSGFERKTSK
     SREKVARRRG DSRGATDRQT NEPKENSNAS LLKLHEKRGE FMNSSLYELV VMCARQCHAD
     KYDKGSQRPS QSKLNQSSSL LSFVLKACLE MFRSLTAKSS GLAIGNLRRT LYEDVKNLAQ
     PIVKLIWWLT LDSEQKNGGF KKNTTQGKRT VENKKDQLYL ALTCFKELFK LSVSEDRSSD
     IIDLLISSAP SNIEDMMEAD QLHDNDTTVT ENPEKRGAHV FLNILKMLYA RALSQSLSRE
     SEAVSELIFG ISRKLHPDQR HLVGHWAAGL CRKNTVQSPT TAQEMVKLAV HLMTTPDDMI
     LVHEMTTELK KLIASGDEES VDSSEAFLIV NCKTKNSLVA VFLHMVDSSL IELEWGLGKL
     KAMLTLGYGS SNVDEDQPAD ERTQRMFLEE ALYSRSTSVV HVLSSFTHMS LKGRLKKYHK
     TPILLHSSIQ SDFTFAYSDS QAEQFLKLTA KFYKLLARIS KSQIAPKGYK QFIPGLKFQK
     MAEVTCRMLT APLYNFVFTL QEVCGTL
//