ID A0A453IWA4_AEGTS Unreviewed; 184 AA.
AC A0A453IWA4;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Ubiquitin-fold modifier-conjugating enzyme 1 {ECO:0000256|ARBA:ARBA00013306, ECO:0000256|PIRNR:PIRNR008716};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET4Gv20706200.1, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET4Gv20706200.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- FUNCTION: E1-like enzyme which specifically catalyzes the second step
CC in ufmylation. Ufmylation is involved in reticulophagy (also called ER-
CC phagy) induced in response to endoplasmic reticulum stress.
CC {ECO:0000256|PIRNR:PIRNR008716}.
CC -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. UFC1
CC subfamily. {ECO:0000256|ARBA:ARBA00008451,
CC ECO:0000256|PIRNR:PIRNR008716}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A453IWA4; -.
DR SMR; A0A453IWA4; -.
DR STRING; 200361.A0A453IWA4; -.
DR EnsemblPlants; AET4Gv20706200.1; AET4Gv20706200.1; AET4Gv20706200.
DR Gramene; AET4Gv20706200.1; AET4Gv20706200.1; AET4Gv20706200.
DR OMA; PLWAKNV; -.
DR OrthoDB; 67279at2759; -.
DR Proteomes; UP000015105; Chromosome 4D.
DR GO; GO:0061657; F:UFM1 conjugating enzyme activity; IEA:InterPro.
DR GO; GO:0071569; P:protein ufmylation; IEA:InterPro.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR014806; Ufc1.
DR PANTHER; PTHR12921; UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1; 1.
DR PANTHER; PTHR12921:SF0; UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1; 1.
DR Pfam; PF08694; UFC1; 1.
DR PIRSF; PIRSF008716; DUF1782; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW Ubl conjugation pathway {ECO:0000256|PIRNR:PIRNR008716}.
FT ACT_SITE 119
FT /note="Glycyl thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR008716-1"
SQ SEQUENCE 184 AA; 20389 MW; 00DF295A06AAC5D3 CRC64;
MEGWDKGTKS VVGEIPLLST RAGPRDGDPW RQRLKEEYRA LIAYTSVNKA KDNDWFRISA
ANPEGTRWEG TCWYVHNLRR YEFPLQFDIP VAYPQVAPEI ELPTLDGKTH KMYRGGKICL
TVHFKPLWAK NCPRFGLAHA LCLGLAPWLA AEVPILVDSG MVKHKDDEAA PADAAAASGS
AAAS
//
