ID   A0A453JF09_AEGTS        Unreviewed;       812 AA.
AC   A0A453JF09;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=DUF4220 domain-containing protein {ECO:0000259|Pfam:PF13968};
OS   Aegilops tauschii subsp. strangulata (Goatgrass).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX   NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET5Gv20012500.2, ECO:0000313|Proteomes:UP000015105};
RN   [1] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=25035499; DOI=10.1126/science.1250092;
RG   International Wheat Genome Sequencing Consortium,;
RA   Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA   Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT   "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL   Science 345:1250092-1250092(2014).
RN   [2] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA   Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA   Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT   "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL   Nat. Plants 3:946-955(2017).
RN   [3] {ECO:0000313|EnsemblPlants:AET5Gv20012500.2}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (MAR-2019) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A453JF09; -.
DR   EnsemblPlants; AET5Gv20012500.2; AET5Gv20012500.2; AET5Gv20012500.
DR   Gramene; AET5Gv20012500.2; AET5Gv20012500.2; AET5Gv20012500.
DR   Proteomes; UP000015105; Chromosome 5D.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR025315; DUF4220.
DR   InterPro; IPR007658; DUF594.
DR   PANTHER; PTHR31325:SF114; DUF4220 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR31325; OS01G0798800 PROTEIN-RELATED; 1.
DR   Pfam; PF13968; DUF4220; 1.
DR   Pfam; PF04578; DUF594; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        39..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        74..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        401..425
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        465..484
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        490..509
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          156..546
FT                   /note="DUF4220"
FT                   /evidence="ECO:0000259|Pfam:PF13968"
SQ   SEQUENCE   812 AA;  92149 MW;  63906CD57B8D258C CRC64;
     LEMTGGNDYT ISSYFTCNAT LHPYVHNLTS SYTDQKNEAF TVTTSIVMFI LAALFFNLNL
     FSRLSNVSAI LNPTVRLFLS TSLSLFLPVM SYLFSEAKKD NATTMTGTGT GSSQLGAELS
     LRARTILMWM LLVELLRKKV EAILVNVGMQ WYSGTIDRAA RIVWLGYLVF YNVKSTGKRV
     IYGTLWVLAA AKLLQRVAIN ELLKRSFAYG RNAQLLNSYM TQMLHEEERR QLLQQQQQRD
     EVGGSELLKM CRYPVIGEDN LERKAGPDGY HLQLPRKNTT VTVGDIWSLP DDKKDKGGLL
     LEDPRLKRLC LSFALYKLLR RRFEDLPITG AETHNCRNLI FKGLHKELLL QGVKATKPQG
     LDVELQGADV AAALFQVFDE EVQFLCEYYH SFLPVVLSNP FFFLANYILF PILVWAFCIL
     TFILCGNGNV HYALQSIKSD NYIISTGAMT LTRCLLRRIG HSPEVLFATI DLSITILLLL
     TFLYEQVWEY LVFILSNWLM VSLLCHYTGK RQWRQSRGLT RLIHCLLWVR SKLSHRNLCF
     KQYSVLCFCP LLPNKAVPKE VKKSILDYLV THIDGHGDGG HAAPLTNGWS ILQSDKHSQY
     RTLLASACEN KSGAEVILIC HIATSLLEVR YPMQNKTLMG SHRKVATTLS KYCAYLVAQY
     PELLPEDKDG TELTYKEMVE DLKKELGGCW RYHLSRQSTR YKKLREIGRP KHATVVVEPP
     PMTTVQTGAK LGRKLIHGAN EHDARVWELL ADFWTELMVY VAPSSSEVHV KAHKEALAQG
     GEFVTVLWAL TTHTGITRPA VKPWTVIPIQ DV
//