ID A0A453JTI3_AEGTS Unreviewed; 931 AA.
AC A0A453JTI3;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Extra-large guanine nucleotide-binding protein 1 {ECO:0008006|Google:ProtNLM};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET5Gv20183000.1, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET5Gv20183000.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
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DR AlphaFoldDB; A0A453JTI3; -.
DR STRING; 200361.A0A453JTI3; -.
DR EnsemblPlants; AET5Gv20183000.1; AET5Gv20183000.1; AET5Gv20183000.
DR Gramene; AET5Gv20183000.1; AET5Gv20183000.1; AET5Gv20183000.
DR Proteomes; UP000015105; Chromosome 5D.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR PANTHER; PTHR10218:SF222; EXTRA-LARGE GUANINE NUCLEOTIDE-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR Pfam; PF00503; G-alpha; 1.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 125..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..33
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..227
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 931 AA; 102158 MW; 69540B5B53B69705 CRC64;
AHAPKKLLSP PHLSPLPTSR VPHLPVPVPH AAPPQTLAPA SLVLRPAADT HGLRRHRRRR
RRVLLRGGVR RPAPLPYSLP RAIPLDLSHI PLAALSSSSS PPPTGSSPLP VVRPLTPSSL
CSAIHAQQHA AGPPRSSGGP AGGGGAQAVA DSPTSVIENH HAAAHHSAEL PSSPSDADDD
DKEEEEGAGM PSVPHQPTVS FAETSCSLLE SSEEEEEEDD DEDETADEAL PAAARSSGSL
SPAHFEAGNH PTGAKSRGCY RCGKGGGFWG RGDKEACLAC GARYCSACVL RAMGSMPEGR
KCLSCIGRPV AESRRNALGR GSRVLRRLIS AAEVELVMRS ERECAANQLR PEDIYVNGAK
LSPEELALLQ GCACPPSRLR PGFYWYDKVS GFWGKEGHKP HCIISANLNV GGALVQKASN
GSTGILVNGR EITKSELQIL KLAGVQCAGK PHFWLNADGS YQEEGQKTVK GKIWDKPIVK
LLSPVLSLPT PNKMTNQCGE EAINVVNRPE YLEQRTTQKL LLVGSGTSTI LKQAKFSYKS
KPFSMDECED LKLIIQSNIY RYIGILLEGR ERFEEEVLAD RRKLCQHDPS SSGRPESGFC
DEEVTEYSIV PRLKAFSDWI LKAMALGNLE DIFPAASREY APLVEELWKD PAIQATYRRR
NELPFLPSAA SYFLDRVVDI SRTEYELCDI DILYADGITS SDGLASTDIS FPQLALDLRV
ADELDPQDTL LRYQLIRINN KGLRENSKWL QMFDDVSLVI FCVAVSDYDE YYEDANGTVV
NKMIESKQLF ESIALHPTFE QMNFLLLLTK FDLLEQKIGK SPLTACDWFA EFTPLVSRNL
IDGTSRSKRG SHNGASLAQM AAHYIGVKFK RLFHSLTERK LYVSYVNALD QQSVCSAIRY
GREIVKWEEE KPVFGSSETV YSGDEPSSYS H
//
