ID A0A453JV24_AEGTS Unreviewed; 608 AA.
AC A0A453JV24;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET5Gv20203200.7, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET5Gv20203200.7}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- SIMILARITY: Belongs to the helicase family.
CC {ECO:0000256|RuleBase:RU363044}.
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DR AlphaFoldDB; A0A453JV24; -.
DR EnsemblPlants; AET5Gv20203200.7; AET5Gv20203200.7; AET5Gv20203200.
DR Gramene; AET5Gv20203200.7; AET5Gv20203200.7; AET5Gv20203200.
DR Proteomes; UP000015105; Chromosome 5D.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR010285; DNA_helicase_pif1-like.
DR InterPro; IPR025476; Helitron_helicase-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10492:SF94; ATP-DEPENDENT DNA HELICASE; 1.
DR PANTHER; PTHR10492; UNCHARACTERIZED; 1.
DR Pfam; PF14214; Helitron_like_N; 1.
DR Pfam; PF05970; PIF1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU363044};
KW DNA damage {ECO:0000256|RuleBase:RU363044};
KW DNA recombination {ECO:0000256|RuleBase:RU363044};
KW DNA repair {ECO:0000256|RuleBase:RU363044};
KW Helicase {ECO:0000256|RuleBase:RU363044};
KW Hydrolase {ECO:0000256|RuleBase:RU363044};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU363044};
KW Reference proteome {ECO:0000313|Proteomes:UP000015105}.
FT DOMAIN 1..95
FT /note="Helitron helicase-like"
FT /evidence="ECO:0000259|Pfam:PF14214"
SQ SEQUENCE 608 AA; 70148 MW; C973CE2ACFBC06F3 CRC64;
MRRRYMDAMA LVRRYGKPDI FLTMTCNPNW DEIRQELYPG QTPQDRPDLV VRVFRAKLEE
LKNKLLKKDI LGKVRAYVYV VEFQKRGLPH AHFLLIMEGR YKLTCPEQYD RLISAELPNK
KKYPELYKLV VKHMMHGPCG ALNLNPECPC TKGRPSCKNH YPRPFHAATL QGKDSYPLYK
RREDGCKAMV RKEWLDNRWV VPYNPHLLRY FNCHINVEAC GSIKAVKYLF KYIYKGHDRA
SIVVSEADKN GDIDEIKQYR DARQLHLPNM HMVSFQAAQN IERVVNHEGV EKSMLTEYFE
ANRLHEDARS ILYRDFPEWY TWQKSQNNKY WRKRVRDTGG QIGRIVSAHP AEGERYYLRV
LLNHVTGATS YEDLRTVNGE ILPTFREAAE RRGLIEGDNT LDESLTESTL YEMPSSLRWL
FATILVFCEP SDVRGLWEKH LDAMSEDYRR SNPSKVAAEQ LVLIDIRNML QSMGKEIESF
PLPDIQEEYD TSIGVTREIF EESTIELNVE DTYLSDSLNS DQRAAYDEIM SAIDRDEGGV
FFVDGPGGTG KTFLYRALLA MVRGQKKIAI ATATSSVAAS IMPGGRTAHS RFKIPLGIDD
GGCCSFTK
//
