ID A0A453K4M1_AEGTS Unreviewed; 835 AA.
AC A0A453K4M1;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET5Gv20284000.12, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET5Gv20284000.12}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR AlphaFoldDB; A0A453K4M1; -.
DR STRING; 200361.A0A453K4M1; -.
DR EnsemblPlants; AET5Gv20284000.12; AET5Gv20284000.12; AET5Gv20284000.
DR Gramene; AET5Gv20284000.12; AET5Gv20284000.12; AET5Gv20284000.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000015105; Chromosome 5D.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd16664; RING-Ubox_PUB; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 3.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR045210; RING-Ubox_PUB.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45958; RING-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR PANTHER; PTHR45958:SF6; U-BOX DOMAIN-CONTAINING PROTEIN 43; 1.
DR Pfam; PF04564; U-box; 1.
DR SMART; SM00185; ARM; 8.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51698; U_BOX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000015105}.
FT DOMAIN 48..127
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
SQ SEQUENCE 835 AA; 91159 MW; A7BD91431848EF6B CRC64;
PRAGAPRPLP PLSALHFPIT RGFECRGVMA DVQDGHYDSS TDSLRVEPIY ESFLCPLTKQ
IMRDPVTLES GATFEREAIL KWFKESDSSG RSLVCPITRK ELSSTELNPS IALRNTIDEW
MHRNEAAKLD VACKSLTSEN SEHDTLQALE YVVEICQRSR SSRHVVRKLG LISLISELLK
NSSTKVRQKA LESLCFVAKD DNDNKDEIAA GDNIRTIVKF LSHGHVQEKE QAASLLYELS
QYKPLSEKIG SVPGAILILV GLSSSKIENL FTVDRADKTL VNLESCEKNV RQMAENGRLQ
PLLRLLLEGS ADTQLSMAAY VGELVLTNDV KVFVAQTAGS ALVNIMKSGN REAREAALKA
LNQISSYDVS AKILIEAGIL PPLIADLFTV GSNQLPMKLK EVSATILANV VASGANFQSI
PLDHNRQTLV SEEIVHNLLH LISNTGPATE CKLLQVLVGL TSSSTTVQGI VDAIKSSGAT
VSLIQFVEAP QREVRMASIK LLNNISPCMG QELAEAFRGN FSQLSSLIRV IADNNGISEE
QAPAAGLVAD LPLQDSVLTR RLVEDGAFTT IISKVIMIRQ GESRGGRFVN PFLEGLVRIV
SRITFILEDD PDIIAVAREY NLTALFSDLL QMNGLDTVQI VSATALGNLS GQSKHLTKIL
PPPNAGLCFS IFPCLSQKSV ETGVCRVHHG ICSSRESFCL LEGKVVEKLV ACLDHNNEKV
VEASLTALST LLDDGVDIDQ GVMVLCDAEG VKPILDVLCE NRTEALRQRA VWAVERILRT
DEIAYEISGN QNVSTALVEA FRHGDFRTRQ IAERALKHVD KLPNFSGIFS KIGAQ
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