ID A0A453K5F8_AEGTS Unreviewed; 2765 AA.
AC A0A453K5F8;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=UBA domain-containing protein {ECO:0000259|PROSITE:PS50030};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET5Gv20304400.7, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET5Gv20304400.7}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR EnsemblPlants; AET5Gv20304400.7; AET5Gv20304400.7; AET5Gv20304400.
DR Gramene; AET5Gv20304400.7; AET5Gv20304400.7; AET5Gv20304400.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000015105; Chromosome 5D.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd14327; UBA_atUPL1_2_like; 1.
DR Gene3D; 6.10.250.1630; -; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR010309; E3_Ub_ligase_DUF908.
DR InterPro; IPR010314; E3_Ub_ligase_DUF913.
DR InterPro; IPR025527; HUWE1/Rev1_UBM.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR11254; HECT DOMAIN UBIQUITIN-PROTEIN LIGASE; 1.
DR PANTHER; PTHR11254:SF398; HECT-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR Pfam; PF06012; DUF908; 2.
DR Pfam; PF06025; DUF913; 1.
DR Pfam; PF00627; UBA; 1.
DR Pfam; PF14377; UBM; 3.
DR SMART; SM00165; UBA; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS50030; UBA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 2743..2763
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1291..1332
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT REGION 924..943
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 990..1032
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1159..1178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1782..1802
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2104..2202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2355..2556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2689..2717
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1000..1017
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1018..1032
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1784..1799
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2104..2127
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2128..2161
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2162..2176
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2177..2202
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2420..2448
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2450..2465
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2475..2492
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2503..2517
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2526..2554
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2765 AA; 304930 MW; 18A9E6E5F7880B8C CRC64;
MAAAAMAAHR ASFPLRLQQI LSGSRAVSPA IKVESEPPAK VKAFIDRVIN IPLHDIAIPL
SGFHWEFNKG NFHHWKPLFM HFDTYFKTYI SSRKDLLLSD DMSESEPLTK NTILQILRVV
QIVLENCQNK TTFAGLEHFK NLLASSDPEV VVAALETLAS VVKINPSKLH MNGKLISCGA
INSHLLSLAQ GWGSKEEGLG LYSCVVANER NQLEGLCLFP ADMENKYDGT QHRLGSTLHF
EYNLAPVQDS DQANDKSSNL CVIHMPDLHL RKEDDLSILK QCIDKFNVPP EHRFALFTRI
RYAHAFNSPR TCRLYSRISL LSFIVLVQSS DAHDELTSFF TNEPEYINEL IRLVRSEDIV
PGPIRALAML ALGAQLAAYA SSHERARILS GSSIISAGGN RMVLLSVLQK AISSLSSPND
TSSPLIVDAL LQFFLLHVLS SSSSGTTVRG SGMVPPLLPL LQDKDPSHMH LVCLAVKTLQ
KLMEYSSPAV SLFKDLGGVE LLSQRLHVEV QRVIGVAEIT SVLASDTSKS EDDHLYSQKR
LIKALLKALG SATYSPANPA RSQSSNDNSL PMSLSLIFQN VGKFGGDIYF SSVTVMSEII
HKDPTCFPAL KELGLPDAFL SSVTAGVIPS CKALICVPNG LGAICLNNQG LESVRETSVL
RFLVETFTSR KYLIPMNEGV VLLANAVEEL LRHVQSLRST GVDIIIEIIN KLSCPRGDKI
TEAARAEEKT DMETDVEGRD LVSAMDSGTD GTNDEQFSHL SIFHVMVLVH RTMENSETCR
LFVEKGGLQT LLTLLLRPTI TQSSGGMPIA LHSTMVFKGF TQQHSTPLAR AFCSSLKEHL
KNALQELDTV FRSCEVTKLE KGAIPSLFIV EFLLFLAASK DNRWMNALLS EFGDVSRDVL
EDIGRVHREV LWQISLFDEK KIEPEASSPS ANEAQQVDAA VGDTDDNRYT SFRQYLDPLL
RRRGSGWNIE SQVSDLINIY RDMGRAATDS HRVGADRYPS TGLPSSSQDQ PSSSSDANAK
SEEDKKRSEH SSCCDMMRSL SYHINHLFME LGKAMLLTSR RENSPINLSP SVVSVASNIA
SIVLEHLNFE GHTISPEREI TVATKCRYLG KVVEFIDGIL LDRPESCNPI MVNSFYCRGV
IQAILTTFEA TSELLFAMNR PPSSPMETDS KTGKEEKDTD CSWIYGPLSS YGAAMDHLVT
SSFILSSSTR QLLEQPIFSG TVRFPQDAER FMKLLQSKVL KTVLPIWAHP QFPECNLELI
SSVTSIMRHV YSGVEVKNNV SNIAARLAGP PPDENAISLI IEMGFSRARA EEALRQVGTN
SVEIATDWLF SHPEEPPEDD ELARALAMSL GNSDTPVQEE DDRTNDLELE EVNVQLPPMD
EVLSSCLRLL QAKETLAFPV RDMLVTISSQ NDGQNRVKVL TYLIDHLKQC LVASDPLKNT
ALSAFFHVLA LILHGDTAAR EVASKAGLVK VVLNLLCSWE LEPREGQTTK VPNWVTSCFL
SVDRMLQLEP KLPDVTELDV LKKDNSPTQT SVVIDDSKKD SESSSSVGLL DLEDQEQLLR
ICCKCIQKQL PSGTMHAILQ LCATLTKVHV AAISFLESGG LHALLSLPTS SLFSGFNSVV
STIIRHILED PHTLQQAMEL EIRHSLVTAA NRHANPRVTP RNFVQNLAFV VYRDPVIFMK
AAQAVCQIEM VGDRPYVVLL KDREKEKSKE KEKDKLVDKD KSSGVATKIT SGDMVMASPV
SAKGKQSDLS ARNMKSHRKP PQTFVTVIEH LLDLVMSFVP PQRAEDQSDG SSSMDMDIDS
SSAKGKGKAV AVTHEESKQA IQDATACLAK NAFVLKLLTD VLLTYASSVQ VVLRHDAELS
STRGPTRTSG GIFNHILQHL LPHATKQKKE RKPDGDWRYK LATRGNQFLV ASSIRSSEGR
KRICSEICSI FVEFTDNTGC KPPMLRMDAY VDLLNDILSA RSPTGSSLSA ESVVTFVEVG
LVQCLTKTLQ VLDLDHPDSA KIVTGIVKAL EVVTKEHVHL ADFNAKGENS SKTVLEQNNV
DSSSNRFQVL DTTSQPTAMV TDHRETFNAV HASRSSDSVA DEMDHDRDID GGFARDGEDD
FMHEIAEDRT GNESTMDIRF DIPRNREDDM AEDEDDSDED MSGDDGEEVD EDDDDEENNN
LEEDDAHQRS HADTDQDDRE IDEEEFDEDL LEEEDDDDED EEGVILRLEE GINGINVFDH
IEVFGGSNNV SGDTLRVMPL DIFGTRRQGR STSIYNLLGR ASDQGVLDHP LLEEPSMLLP
QQRQPENLVE MAFSDRNHEN SSSRLDAIFR SLRSGRNGHR FNMWLDDGPQ RNGSAAPTVP
EGIEELLLSQ LRRPMAEHPD EQSTPAVDAQ VNDPPSNFHG PETDAREGSA EQNENNENVD
IPAVRSEVDG SASAGPAPPH SDELRRDASN ASEHVADMQY ERSDTAVRDV EAVSQASSGS
GATLGESLRS LDVEIGSVEG HDDGDRHGAS DRTPLGDVQA ATRSRRPSGN AVPVSSRDIS
LESVREIPPN TVQESDQNAS EGDQEPNRAT GTDSIDPTFL EALPEDLRAE VLSSRQNQVT
QTSSEQPQHD ADIDPEFLAA LPPDIREEVL AQQRAQRLQQ QSQELEGQPV EMDAVSIIAT
FPSEIREEVL LTSPDTLLAT LTPALVAEAN MLRERFAHRY HSGSLFGMNS RNRRGESSRR
GDIIGSGLDR NTGDSSRQTA SKLIETVGTP LVDKDALNAL IRLLRVVQVI PFLCLVVLLF
LVVHA
//
