ID A0A453KD77_AEGTS Unreviewed; 631 AA.
AC A0A453KD77;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=EGF-like calcium-binding domain-containing protein {ECO:0000259|SMART:SM00179};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET5Gv20379700.12, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET5Gv20379700.12}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, clathrin-coated vesicle
CC membrane {ECO:0000256|ARBA:ARBA00029430}; Single-pass type I membrane
CC protein {ECO:0000256|ARBA:ARBA00029430}. Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004614}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004614}. Prevacuolar compartment membrane
CC {ECO:0000256|ARBA:ARBA00043947}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00043947}.
CC -!- SIMILARITY: Belongs to the VSR (BP-80) family.
CC {ECO:0000256|ARBA:ARBA00007038}.
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DR AlphaFoldDB; A0A453KD77; -.
DR STRING; 200361.A0A453KD77; -.
DR EnsemblPlants; AET5Gv20379700.12; AET5Gv20379700.12; AET5Gv20379700.
DR Gramene; AET5Gv20379700.12; AET5Gv20379700.12; AET5Gv20379700.
DR Proteomes; UP000015105; Chromosome 5D.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd02125; PA_VSR; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR PANTHER; PTHR22702; PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22702:SF1; PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF02225; PA; 1.
DR SMART; SM00179; EGF_CA; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR PROSITE; PS01187; EGF_CA; 1.
PE 3: Inferred from homology;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 575..594
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 521..563
FT /note="EGF-like calcium-binding"
FT /evidence="ECO:0000259|SMART:SM00179"
SQ SEQUENCE 631 AA; 69933 MW; 49C39A32F046FF2C CRC64;
GRFVVEKNSL KVTAPDSLKG SYECAIGNFG VPQYGGTMVG VVAYPKSNRK ACKSFDDFDI
SYKAKPGSLP TFLLVDRGDC FFTKKAWNAQ NAGVAAILVA DDKDEPLITM DTPEESGRAD
YLENITIPSA LITKSFGDRL RKAVDGGHMV NVNLDWRESL PHPDERVEYE FWTNSNDECG
PKCDSQIDFV KSFKGPAQIL EKKGYTQFTP HYITWYCPEA FTLSKQCKSQ CINHGRYCAP
DPEQDFSKGY DGKDVVVQNL RQVCVYKVAK ENKKPWLWWD YVTDFAIRCP MKEKKYTKEC
ADGVIKSLGL DHKAIDKCIG DPNADEENHV LKAEQDAQIG KGARGDVTIL PTLVINNRQY
RGVCSVKPPK QFSIATSKLR GSGCAYPNIC FAGKLDKGAV LKALCAGFQE TTEPAVCLSE
DIQTNECLEN NGGCWHDKAA NISACKDTFR GRVCECPVVK GVKFVGDGYT HCEASGSGRC
EINNGGCWKE TRNGRTHSAC TDGGCKCPDG FKGDGVHKCE DVDECKERTA CQCKECKCNN
TWGSYECGCG GGFLYMKEHD TCISKDAGAR VGWNFLWFLL FGLAAVGIAG YAVYKYRIRS
YMDSEIRAIM AQYMPLDNQG EIPNHSHHIE M
//
