ID   A0A453LMF6_AEGTS        Unreviewed;       855 AA.
AC   A0A453LMF6;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   RecName: Full=DUF4220 domain-containing protein {ECO:0000259|Pfam:PF13968};
OS   Aegilops tauschii subsp. strangulata (Goatgrass).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX   NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET5Gv20840500.3, ECO:0000313|Proteomes:UP000015105};
RN   [1] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=25035499; DOI=10.1126/science.1250092;
RG   International Wheat Genome Sequencing Consortium,;
RA   Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA   Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT   "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL   Science 345:1250092-1250092(2014).
RN   [2] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA   Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA   Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT   "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL   Nat. Plants 3:946-955(2017).
RN   [3] {ECO:0000313|EnsemblPlants:AET5Gv20840500.3}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (MAR-2019) to UniProtKB.
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DR   AlphaFoldDB; A0A453LMF6; -.
DR   STRING; 200361.A0A453LMF6; -.
DR   EnsemblPlants; AET5Gv20840500.3; AET5Gv20840500.3; AET5Gv20840500.
DR   Gramene; AET5Gv20840500.3; AET5Gv20840500.3; AET5Gv20840500.
DR   Proteomes; UP000015105; Chromosome 5D.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR025315; DUF4220.
DR   InterPro; IPR007658; DUF594.
DR   PANTHER; PTHR31325; OS01G0798800 PROTEIN-RELATED; 1.
DR   PANTHER; PTHR31325:SF127; OS02G0243700 PROTEIN; 1.
DR   Pfam; PF13968; DUF4220; 1.
DR   Pfam; PF04578; DUF594; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          43..478
FT                   /note="DUF4220"
FT                   /evidence="ECO:0000259|Pfam:PF13968"
FT   REGION          804..855
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        804..821
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   855 AA;  97498 MW;  5061ED891D67CB4C CRC64;
     VEWWEEWHLR ILVLSSLFIQ YLLLCSAPLR KFAIPSWYRS IIWLAYQGSD AVAIYALATL
     FNRQRSQDHG SGTSANNSSI LEVVWAPVLL MHLGGQDLIT AYNIEDNELW TRHILTAVSQ
     VTVAIYMFCK SWPGGDKRLL QASILFFVPG ILKCIEKPWA LKSASINSLV SSSCHAPRRT
     ATREDEINSL EDYVQKARAF AQTDPGFQAQ EGDAVNHGAD NYLSQSQGED IVVDLEANHG
     SQTQGVAATV DLEPDHHPQT SRTWIGRLNQ IKEKMGSHVS QIMEKRRSHL NQREPRLRRR
     DNDYNGDPET YRIFVDLASP YPDRLVILKS FWVLDGKQAY ILLQNRLFSI FNLLYTKSKI
     LGSFKEEEDP SGLELLSLYI RLSASLLPWA AIGLFHKSHR EAYDDNDVKV TYALFCCTAV
     LEYCSCASFA FAKFTFLKVF LNAILKVKDS LIGQFNLVGF FARNRRHSRK MCIVNFFNCK
     DFLDQNWSMK PCKLSFAILD LVLKYVKKGW EDQIKDTDSY WKFNDRRGQW TLQSNNCDKD
     LSCSLRKPFD ESVLLWHIAT DFCFYYMGAS AYHQCATAQC IQDASGEGHG CAVWCERSHH
     HKRAIQCREI SNYMMYLLFV NPEMLLPGTR RNLFTAANSE LKKILKDDNA SLKKIVKGGK
     PSLMEILKCN KPFCNFFTVK RPSLKEIERG FTQRIIAKVQ PRENREQVVE HTDLPLDAET
     DATTQEGFVH DAWNLANGLL QMRDEKMWEV IEGVWVEMLC FSASRCRGYL HAKSLGTGGE
     LLTYICLLLS HMGMETLPER LQRTELSSGG NARVTPLTSQ VPGSEDPPPL RRWRPHEAAA
     AGASTSRPQE IQPAE
//