ID A0A453LN04_AEGTS Unreviewed; 890 AA.
AC A0A453LN04;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Amino acid permease/ SLC12A domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET5Gv20852900.11, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET5Gv20852900.11}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A453LN04; -.
DR EnsemblPlants; AET5Gv20852900.11; AET5Gv20852900.11; AET5Gv20852900.
DR Gramene; AET5Gv20852900.11; AET5Gv20852900.11; AET5Gv20852900.
DR Proteomes; UP000015105; Chromosome 5D.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR018491; SLC12_C.
DR InterPro; IPR004842; SLC12A_fam.
DR NCBIfam; TIGR00930; 2a30; 1.
DR PANTHER; PTHR11827:SF104; CATION-CHLORIDE COTRANSPORTER 1; 1.
DR PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR Pfam; PF00324; AA_permease; 1.
DR Pfam; PF03522; SLC12; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 33..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 309..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 349..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..417
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 423..445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..495
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 38..513
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT DOMAIN 555..676
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT DOMAIN 685..889
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 890 AA; 97772 MW; DCFAA8B522FF318D CRC64;
SMTGEETQAP SSPREGEDVA ITIGRPKETG PKFGTMMGVF VPCLQNILGI IYYIRFTWIV
GMAGVWQSLV LVSFCGACTF LTGLSLSAIA TNGAMKGGGP YYLIGRALGP EVGISIGLCF
FLGNAVAGSM YVLGAVETFL DAVPSAGLFQ ESVTVVNNTL INGTATAGTA TISTPSLHDL
QVYGVIVTIL LCFIVFGGVK IINKVAPAFL IPVLFSLLCI YLGVFIAPRH NAPKGITGLS
LTSLRDNWGS EYQRTNNAGV PDPNGSIYWG FNALVGLFFP AVTGIMAGSN RSASLKDTQR
SIPIGTLSAT LTTTAMYLLS VLLFGALSTR EELLTDRLLT ATVAWPTPVV IYIGIILSTL
GAALQCLTGA PRLLAAIAND DILPVLNYFK VSEGVEPHAA TLFTALICIG CVIIGNLDLI
TPTITMFFLL CYAGVNLSCF LLDLLDAPSW RPRWKYHHWS LSLVGALLCV VIMFLISWSF
TVISLALASL IYYYVSLKGK AGDWGDGFKS AYFQLALRSL RSLGANQVHP KNWYPIPLIL
CRPWGKLPEN VPCHPKLADF ANCMKKKGRG MSIFVSTIDG DYHELAEDAK TACHQLEAYI
EYKQCEGVAE IIVAPSMSEG FRSIVQTMGL GNLKPNIVVV RYPEIWRREN LTEIPSTFVS
IINDCIIANK AVVIVKGLDE WPNEFQRQYG TIDLYWIVRD GGLMLLLSQL LLTKATFESC
KIQVFCIAEE DTDAAELKTD VKKFLYDLRM HAEVIVVTMK SWESHVENSS SSAQPDDSQE
AYTSARRRIS AYLSEMKETT EREGRPQMVD GKQAVVNEEK VDKFLYTMFK LNSTILRHSR
MAAVVLVSLP PPPLNHPAYF YMEYMDMLVE NVPRMLIVRG YRRDVVTFFT
//
