ID A0A453LRU9_AEGTS Unreviewed; 387 AA.
AC A0A453LRU9;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Magnesium transporter {ECO:0000256|RuleBase:RU366041};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET5Gv20891600.10, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET5Gv20891600.10}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- FUNCTION: Magnesium transporter that may mediate the influx of
CC magnesium. {ECO:0000256|RuleBase:RU366041}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU366041}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU366041}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC
CC 1.A.35.5) family. {ECO:0000256|ARBA:ARBA00007535,
CC ECO:0000256|RuleBase:RU366041}.
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DR AlphaFoldDB; A0A453LRU9; -.
DR EnsemblPlants; AET5Gv20891600.10; AET5Gv20891600.10; AET5Gv20891600.
DR Gramene; AET5Gv20891600.10; AET5Gv20891600.10; AET5Gv20891600.
DR Proteomes; UP000015105; Chromosome 5D.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:UniProt.
DR CDD; cd12823; Mrs2_Mfm1p-like; 1.
DR Gene3D; 2.40.128.330; -; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 1.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR InterPro; IPR039204; MRS2-like.
DR PANTHER; PTHR13890:SF31; MAGNESIUM TRANSPORTER MRS2-I; 1.
DR PANTHER; PTHR13890; RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL; 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|RuleBase:RU366041}; Magnesium {ECO:0000256|RuleBase:RU366041};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU366041};
KW Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU366041};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU366041}; Transport {ECO:0000256|RuleBase:RU366041}.
FT TRANSMEM 322..343
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366041"
FT TRANSMEM 355..379
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366041"
FT REGION 113..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 187..214
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 123..138
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 387 AA; 42719 MW; 79FED16FA808A751 CRC64;
MAAAGGEAAA AALAAAKKRA ASRSWILFDA AGEERELDAD KYAIMHRVDI NARDLRILDP
LLSYPSTILG RNSHRRVDQH IKAIVTSEEV LLRDPSDENV IPVVEELRRR LAPSSAAQHD
GKDNLSGQHD AEAAEEDESP FEFRALEVTL EAICSFLDAR TTELETNAYP ALDDLTSKIS
SHNLDKVRKL KSGMTRLTAR VQKVRDELEQ LLDDDDDMAD LYLSRKLAGA SSPVSGSGGP
NWFPASPTIG SKISRASRAS AATIHGNEND VEELEMLLEA YFMQIDGTLN KLTTLREYID
DTEDYINIQL DNHRNQLIQL ELFLSSGTVC LSLYSLVAGV FGMNIPYTWN DGHGYVFKWV
VIVSGLFCAF MFVTIVAYAR HKGLVGS
//
