ID   A0A453M3Y2_AEGTS        Unreviewed;      1098 AA.
AC   A0A453M3Y2;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=NB-ARC domain-containing protein {ECO:0000259|Pfam:PF00931};
OS   Aegilops tauschii subsp. strangulata (Goatgrass).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX   NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET5Gv21032000.3, ECO:0000313|Proteomes:UP000015105};
RN   [1] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=25035499; DOI=10.1126/science.1250092;
RG   International Wheat Genome Sequencing Consortium,;
RA   Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA   Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT   "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL   Science 345:1250092-1250092(2014).
RN   [2] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA   Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA   Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT   "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL   Nat. Plants 3:946-955(2017).
RN   [3] {ECO:0000313|EnsemblPlants:AET5Gv21032000.3}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (MAR-2019) to UniProtKB.
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DR   AlphaFoldDB; A0A453M3Y2; -.
DR   EnsemblPlants; AET5Gv21032000.3; AET5Gv21032000.3; AET5Gv21032000.
DR   Gramene; AET5Gv21032000.3; AET5Gv21032000.3; AET5Gv21032000.
DR   Proteomes; UP000015105; Chromosome 5D.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR   PANTHER; PTHR23155:SF1058; OS11G0682501 PROTEIN; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        79..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          435..658
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
SQ   SEQUENCE   1098 AA;  125856 MW;  548E2BEB4B56E61E CRC64;
     SLYLSRLDSA VCGTGSKDKI PFRFGLCSSY AARSDSLFFH AQFSARVSRR QGYITVQWST
     DHGSFFTPGL PLVSFSKSIA SMGAFVNGLA VAAVGWWLAP VITFLLNKLL AYLYDASQDF
     IDMRSGTMPR LRFTLGEVME QRMLIKLSKK ESDVTTKLSG LDSLLKKLKD ALYEAEDILD
     LVDYHRIEKE VGKAGSSTWL QWCWQRLCDI TREKSAWLLQ RAKQSLCWLR GCLHIAGDTS
     APLLQWVHER FCWLWPWVRV AGQRTAPLLQ LAKKGLCWLW GCVTGPGELL PSASAPSTSL
     VQRISSCCSC IFHWLTTKTT RAIEGARYYR DWSLDELGFT RYQQAVVMES NCIMMGPLYI
     LLKKNMKKVE KLIDEAQEIF TLKNKVQETI GQANQQRRNK LGTLTADVST GDRQKTTAYP
     VGKITGRDNI CQDIRTMLHA SKSDVVGIYG IAGSGKTTLA QYVCNAMKEE EGEKEERKHH
     FHLFMWIHVT QKFSVHAIFS EMLEAASGKK AEYASLDVMQ KKLEHELSTK RFLLVLDDVW
     CNKDADDQNL QQLIFPLKFG LEGSKILATS RNKGAFAALS PEVTYTSVPI PDLNDEDFRE
     MFMYYALGSS GLLDPMLGEL EEIGAEIAKK LKRLPLAART VGGQLRRKQD VWFWRSVQVR
     DLLNETTGAL WWSYQQFDEH VRQCFAYCSI FSRRHHFKRD ELVQFWMAGA FIETTNVAQD
     LYDVGQNYFD ELLSASFLQL GERQVEFGCE VDYFTIHDLL HDLAEEAARG DCFRIEEGVT
     EEVPPDVRHL FVESCDIKML TEKIYELQNL RTLIIDCYIN IGSRDEKVFE RMFRRLKKLR
     VLVLHLAAGD GNIISLPACI GLLKHLSMEN FPDIGRLKWL RKLVRFSVSK TQGYELRQLK
     DLSKLAGALS ITGLENVQSK EESIEASLAH KDRLRELKLS WKDTSCSPEV EAEVLEGLCP
     PKYLERLEVW NYHGSKYPDW MVGQQNGGPK HLRNLWLHSC CRLEQAPQLF EVFLHLRWFR
     LYFSNWHSLP DNMERLASLL LLDINRCPNI QSLPALPSSL ERFYLRSCSE ELMRSCETIG
     HPNWQKIQRI PDISIIRD
//