ID A0A453M9J1_AEGTS Unreviewed; 893 AA.
AC A0A453M9J1;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Disease resistance protein RPM1 {ECO:0008006|Google:ProtNLM};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET5Gv21107900.3, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET5Gv21107900.3}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR AlphaFoldDB; A0A453M9J1; -.
DR STRING; 200361.A0A453M9J1; -.
DR EnsemblPlants; AET5Gv21107900.2; AET5Gv21107900.2; AET5Gv21107900.
DR EnsemblPlants; AET5Gv21107900.3; AET5Gv21107900.3; AET5Gv21107900.
DR Gramene; AET5Gv21107900.2; AET5Gv21107900.2; AET5Gv21107900.
DR Gramene; AET5Gv21107900.3; AET5Gv21107900.3; AET5Gv21107900.
DR OMA; VNTHELC; -.
DR OrthoDB; 356354at2759; -.
DR Proteomes; UP000015105; Chromosome 5D.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1123; NB-ARC DOMAIN CONTAINING PROTEIN, EXPRESSED; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000015105}.
FT DOMAIN 13..85
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 149..283
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 893 AA; 99356 MW; B11556BE8BC66396 CRC64;
MEVAVVVGPI VRLLPKLLSV VDGKRKQLDN LEVDAGFIRR DLQSIQEIIG RSSGGRPITD
LWIRDLRRLA DDMEDCIDRF QVGKMSRIRF VGKIARLKKR SKDTLEQLQN FISIAGAPPA
APDHPAGGTE DPEEQLLALL TRSQSEARRG ELKVITVAGF GGVGMTRLAH KVYSDRDVRS
QFPLHAWVRA APGINLLQEI HDQLLPILTK RQAEHGASSS SSKSIPQVNG DVEHGAIDHR
LAGLLKTTRY LIVIDGVNTH ELCGILSSIS WADGVDGRII MTTAIQLPAA TCCRCGDGSS
LAMGSTSQVF IGELTESGFV EACHHLRDDT LARMQRSNNE ILSNPVVQDL LLYFCIFPRD
HPVKRNPLIR RWLAEGLVFP QQETECFSQD VAAKNLESLI SRDVIQPIQV RNYGSVKKCQ
TSGMMLNSIS SKSNSQNFIT MLCGSKTTEK DPPGKDIRRL SLHLNSAANG PRNLPKDLSR
LHSLAVFPDD ANITRHQPNL NYAKYKLLRV LDLKECADVR AKHVGKICDL LLLKYLSFGD
SVDEVPRKIA KLKWLETLDM RRTKVVTLPI EVFQLPGLKH LLGKFQLAEG DSTQKLEELL
TKDSELQRLS GFVIGKSEEF AQLMGHMAKL RKVKIWCDST ADVTKLAHVL GATKKFIRDG
MDMTRVDRSL SIDFQGCPTE CSEQFMDSLQ AEGRLTSLKL CGKLTRLPQF HANTNYIEEL
CLSRTNLRGD TILSGLSALR MKLKYLKLVE DELGQLVIKP EHFRSLRGLC LVGERSMEDI
TIQDEAVPYL VSLHIFCEAL GDLPGIDITH MARLKEVALH SGVQETIKDG WQAAAMNHPN
RPKVLFIHPA NSRQRDPPML CGATGETANW TKPIGRKFAT SIMGGIFCCV RPS
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