ID   A0A453PTS1_AEGTS        Unreviewed;       870 AA.
AC   A0A453PTS1;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding domain-containing protein {ECO:0000259|SMART:SM01002};
OS   Aegilops tauschii subsp. strangulata (Goatgrass).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX   NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET6Gv20854500.16, ECO:0000313|Proteomes:UP000015105};
RN   [1] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=25035499; DOI=10.1126/science.1250092;
RG   International Wheat Genome Sequencing Consortium,;
RA   Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA   Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT   "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL   Science 345:1250092-1250092(2014).
RN   [2] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA   Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA   Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT   "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL   Nat. Plants 3:946-955(2017).
RN   [3] {ECO:0000313|EnsemblPlants:AET6Gv20854500.16}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (MAR-2019) to UniProtKB.
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DR   AlphaFoldDB; A0A453PTS1; -.
DR   EnsemblPlants; AET6Gv20854500.16; AET6Gv20854500.16; AET6Gv20854500.
DR   Gramene; AET6Gv20854500.16; AET6Gv20854500.16; AET6Gv20854500.
DR   Proteomes; UP000015105; Chromosome 6D.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006553; P:lysine metabolic process; IEA:UniProt.
DR   CDD; cd12144; SDH_N_domain; 1.
DR   Gene3D; 1.10.1870.10; Domain 3, Saccharopine reductase; 1.
DR   Gene3D; 3.30.70.2690; LOR/SDH bifunctional enzyme, conserved domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR007698; AlaDH/PNT_NAD(H)-bd.
DR   InterPro; IPR007545; LOR/SDH_bifunc_enz_cons_dom.
DR   InterPro; IPR043009; LOR/SDH_bifunc_enz_cons_dom_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR032095; Sacchrp_dh-like_C.
DR   InterPro; IPR005097; Sacchrp_dh_NADP.
DR   PANTHER; PTHR11133; SACCHAROPINE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11133:SF22; SACCHAROPINE DEHYDROGENASE [NADP(+), L-GLUTAMATE-FORMING]-RELATED; 1.
DR   Pfam; PF04455; Saccharop_dh_N; 1.
DR   Pfam; PF16653; Sacchrp_dh_C; 1.
DR   Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR   SMART; SM01002; AlaDh_PNT_C; 1.
DR   SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015105}.
FT   DOMAIN          31..216
FT                   /note="Alanine dehydrogenase/pyridine nucleotide
FT                   transhydrogenase NAD(H)-binding"
FT                   /evidence="ECO:0000259|SMART:SM01002"
SQ   SEQUENCE   870 AA;  96309 MW;  D97B00491F34930F CRC64;
     MDFHLEFVQL YLHSPDPEMV IPAFIAFTFR LLAAAHLLTF ITSYVTVSQG AQEIFKLLPH
     TFVDAEKLPE LSAGKSLPPH HQSTRRAFQL YGCVVTSKDM VAPKDPSRCF DKADYYAHPE
     HYRPVFHERI APYASAIVNC MYWERRFPRL LSIDQLQQLM KNGCPLVGIS DITCDIGGSI
     EFVNKSTSIE RPFFRYDTST NLYHDDMEGD GVICLAVDIL PTEFSREASQ HFGDILSRFV
     TSLASAKGLL ELPSHLRRAC IAYTGKLTPL YEYIPRMRKT MIELPPTPAN SLPDKKYTTL
     VSLCGHLFDK FLINEALDII ETAGGSFHLV KCDVGQSIDD MSYSELEVGA DDTTTLDKII
     DSLTSIANAH RGDPNAAEIS LKIGRVSECG IDDSMDKVGP KVLILGAGRV CRPAAEFLTS
     YQNIDQVHVV VASLYQKDAE ETVDGIKNAT AAQLDVSDTE SLSNLVSQVD VVVSLLPASF
     HAAIARVCIE LKKHLVTASY VDDSMSKLEQ AAQGAGVTIL CEMGLDPGID HMLSMKMIDE
     AHALNGKIKA FTSFCGGLPS PAAANNPLAY KFSWSPAGAI RAGRNPAVYK FLGEIIDVDG
     SKLYESAKRL RLPELPAFAL EHLPNRNSLM YGDLYGISKE ASTVYRSTLR YEGFSEIMAI
     LAKIGFFDAE NHPLLQETDR PTYRIFLNDL LDVNNVSTSN TKVNGEETGG HDDELISRLM
     MLGHCKEKEL AVKILKTIKF LGLHEETQIP KDCSSAFTVI CQRMEQRMAY GHNEQDMVLL
     HHEVEVEYPD GRPTEKHQAT LLEFGKTENG RPTTAMALTV GVPAAIGALL LLQNKVQRKG
     VIRPLEPEIY IPALEILEAS GIKLIERVET
//