ID   A0A453Q4J8_AEGTS        Unreviewed;       921 AA.
AC   A0A453Q4J8;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Disease resistance N-terminal domain-containing protein {ECO:0000259|Pfam:PF18052};
OS   Aegilops tauschii subsp. strangulata (Goatgrass).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX   NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET6Gv20974500.4, ECO:0000313|Proteomes:UP000015105};
RN   [1] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=25035499; DOI=10.1126/science.1250092;
RG   International Wheat Genome Sequencing Consortium,;
RA   Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA   Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT   "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL   Science 345:1250092-1250092(2014).
RN   [2] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA   Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA   Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT   "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL   Nat. Plants 3:946-955(2017).
RN   [3] {ECO:0000313|EnsemblPlants:AET6Gv20974500.4}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (MAR-2019) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC       {ECO:0000256|ARBA:ARBA00008894}.
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DR   AlphaFoldDB; A0A453Q4J8; -.
DR   EnsemblPlants; AET6Gv20974500.4; AET6Gv20974500.4; AET6Gv20974500.
DR   Gramene; AET6Gv20974500.4; AET6Gv20974500.4; AET6Gv20974500.
DR   Proteomes; UP000015105; Chromosome 6D.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR   CDD; cd14798; RX-CC_like; 1.
DR   Gene3D; 1.20.5.4130; -; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR038005; RX-like_CC.
DR   InterPro; IPR041118; Rx_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR   PANTHER; PTHR23155:SF1240; OS11G0655200 PROTEIN; 1.
DR   Pfam; PF18052; Rx_N; 1.
DR   SUPFAM; SSF52058; L domain-like; 1.
PE   3: Inferred from homology;
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..40
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           41..921
FT                   /note="Disease resistance N-terminal domain-containing
FT                   protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5019438998"
FT   DOMAIN          82..163
FT                   /note="Disease resistance N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18052"
FT   REGION          357..378
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          888..921
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        359..378
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        888..907
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   921 AA;  102896 MW;  457C9181F8EE74D9 CRC64;
     RRRGKPTVGA NGAKTNTYTM LVMLQVQSLS LLLPASCCLA APKSQVPTTP PIQQCLSSPL
     LFASIDAHTT SSKSSTMDAQ GALDSLLGRL TTILVDEAKL LGNLHGDVEF IKEEMECMNG
     VLLHLAEAQH LDRHVRAWMK QVVGLARNCE GNVELYIHSV TDAGHHDRGF LGYLRQIIRY
     MRTIPERHRI ATRIRELKVR AHDVGHRQLR YGITMPPAAD QDGAIFMDDD IAVPDGPEAE
     LEDARRRALL VNCSWSEDKE AYEQKIMDDT IKSLLLSEEE PVDELANGES HPRIFLMTWD
     ECSGEDRDFT ILVAKKLYEQ EISSFSCKAR VSHYKLDSVV VLLQEILHQV TSLPAEQEDV
     PRLEAEKSTE TSLGDDEDGE AMQLTKKLEG FLKEGCRDAN KSVAKQMVKI SYNDLPAKYR
     SCLLYLTIFP DGDPIRRTTV CTRWIAEGLI TSRENHAQDE ADSCIDALLS RGLIQPGQIS
     DTGKIKTFTL HRVVREVITM IARDVNFVDT DLPPDLARHL PVHSRTGVQT SHADRSMKAA
     DGNGIVAFLP DLAKSSQWQL MKMLDLEGCR GLKKHHLKSI CKIILLKYLS LRNTDITELP
     KQIEKLQCLE TFDIRQTAVQ SFATKSIMVP MLKHLLAGQA ESPSNNSDGP QDLFTAVRLP
     SSIRRMEQLE TLSHVEASHR LSDLTDVGHL LRLRKLGVIL SGKKGALDIL FQQIERLHGC
     LRSLSIQINQ PVSKNEDTPC AEEVITLVSP PKLLQSLNIR GIRSDLLMWI AELDQLTKIT
     LSETYLAEDY TRILGKLAAL RCLRLRRNSY AGSRLTFKDE EFKSLKSLVV DDGIIINISF
     DTGAAPKIEA VVWYFATMES ISGLLCLPKL KKLELNGDCD PDAVRQELDE EHPNSVDFKH
     RPGHGHQEDG ATVAASTSMS K
//