ID A0A453QD93_AEGTS Unreviewed; 1510 AA.
AC A0A453QD93;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Disease resistance protein RPM1 {ECO:0008006|Google:ProtNLM};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET7Gv20048900.7, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET7Gv20048900.7}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EnsemblPlants; AET7Gv20048900.2; AET7Gv20048900.2; AET7Gv20048900.
DR EnsemblPlants; AET7Gv20048900.7; AET7Gv20048900.7; AET7Gv20048900.
DR Gramene; AET7Gv20048900.2; AET7Gv20048900.2; AET7Gv20048900.
DR Gramene; AET7Gv20048900.7; AET7Gv20048900.7; AET7Gv20048900.
DR Proteomes; UP000015105; Chromosome 7D.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155:SF1121; DISEASE RESISTANCE PROTEIN RGA5; 1.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000015105}.
FT DOMAIN 559..641
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 736..942
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT REGION 384..426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1487..1510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..426
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1510 AA; 170462 MW; 38104B3A357D874D CRC64;
MMTQVRSLIF FGFLNCVPSF VEYKLLRVLI LHIWADQSKI FDLTRISELF QLRYLKIDCN
ITVHLPDEIQ QLRFLETLEL HAPVSDMPSD ISCLPLLRTL GYFDLGKNSI ENVQSLGELN
NLQDLHLTWS NIADPDNLKN NMQCLGSILR KLSNLKSLTL VRAASSHPDV LDDAGGAILG
ITGDVLSSVS SPPPLLQRLE LSGRCCIFAS LPEWTKELGN LCILKISVRK LLRKDIDILK
GLPALMALSL YVWTAPVGKV VFDSEGFSIL KYFRFTCAAP CLAFLIGSMP SVRELKLAFN
ANRMEQYSQI VAGLEYLIEL KEITAKVGGT GADESDKRYA VSALSGAIAN HPCSPIITVQ
CVDRILYGED DTSAVTQEQE HWTLEEEHEM QEESLDPLPE LVPIPSTQTQ MRDGSQNGGT
DSSREVLTQT REGVQDELIE RSMEVLTYEQ EHVTLERQHE IHEELLDPLP EVLSTSSTQT
QVREEVRDGE IERSMEVLTQ EQEQHTLEQQ DDMTDRVLNV QIGTLMEVLA QEEQWRNNMQ
NSGIGRSMAV VSASHGTLDP LLDKLNALLA EEYGNLEGVL HEVSALKSEL TLMHTAVRKY
TMLEDPDVQV KLWLSLLREF SYDAEDYIDK FIHQLDNGGH HGGFKQIFGK TACQLKTLGS
QHEIAEKIDE LKDRAKNLKA SSYKMDDTAC ITSCHSTVDP QLAALFVDSA HLVGIDSPRD
DLAKWTVEVG NSSAKHHCRM LSIVGFGGLG KTTLANEVYR KAKGHFHCQA FVSVSQKPDI
KKILMNLISQ VSPHGFTKDT YNWDKMRLIR ELRELLKDKR YLVVIDDIWS ISAWNIIKCA
FPENNCSSRV ITTTRIIEVA RSCCMGQDDR MYEMQPLSDF HSKRLFLRRI FGSKDSPDML
EEVSNEILKK CGGLPLAIIS VSSLLANRPA NKEEWEKVSA LDKDIGLEEM NRILCLSYNA
LPDNLKTCLL YLSNFPEGCV IERERLVRRW IAEGFISENH GQSQQEVAEW YFYELINRSM
IQAVDICYDG KARACRVHNM MLELIISKSA EDNFVMVIRS RQTGLVNRHG CIRRLSVQHI
DQNIASVLAN EDLSHVRSLT VTSSSCIEHL PSLACFENLR VLDFEGCDGL EKYHMKGLGK
FFQLKYLSLR GTWISHLPSE VVMLRNLETL DIRETHVEEL PAEIVHLTKL QHLIASTDYV
MPGIKIPDGI GNMRNLRVLL GCGISSGSVG ALEELGNLTN LNELDVQYWG IGSEYKRHED
RFLSSLIKLG SCKLQSFRIW RKCPGDVKFL ESWLPPPFSL QRFEMSGCYS FKWIPCWISP
ALTSLAYLEI NIVEVTQTDL CILGEMPALL HLGLTCQTFR KERLIFYSRG FQHLKEFVYD
VSVLPSGNLL FMEGALPMLE DLSLIYCVSM VNAYGFFLGI EHLPRLKNAQ VRLYKQGAAS
SDIASAEVTI RNEADDNPNR PRVTLVEHVK REDYCSDGCP NRTVAVEGLD ANTTNQKGGS
RKTTNQTTNR
//
