ID   A0A453QEL2_AEGTS        Unreviewed;       914 AA.
AC   A0A453QEL2;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=DUF4220 domain-containing protein {ECO:0000259|Pfam:PF13968};
OS   Aegilops tauschii subsp. strangulata (Goatgrass).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX   NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET7Gv20081200.1, ECO:0000313|Proteomes:UP000015105};
RN   [1] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=25035499; DOI=10.1126/science.1250092;
RG   International Wheat Genome Sequencing Consortium,;
RA   Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA   Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT   "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL   Science 345:1250092-1250092(2014).
RN   [2] {ECO:0000313|Proteomes:UP000015105}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX   PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA   Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA   Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT   "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL   Nat. Plants 3:946-955(2017).
RN   [3] {ECO:0000313|EnsemblPlants:AET7Gv20081200.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (MAR-2019) to UniProtKB.
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DR   AlphaFoldDB; A0A453QEL2; -.
DR   STRING; 200361.A0A453QEL2; -.
DR   EnsemblPlants; AET7Gv20081200.1; AET7Gv20081200.1; AET7Gv20081200.
DR   Gramene; AET7Gv20081200.1; AET7Gv20081200.1; AET7Gv20081200.
DR   Proteomes; UP000015105; Chromosome 7D.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR025315; DUF4220.
DR   InterPro; IPR007658; DUF594.
DR   PANTHER; PTHR31325:SF23; EXPRESSED PROTEIN; 1.
DR   PANTHER; PTHR31325; OS01G0798800 PROTEIN-RELATED; 1.
DR   Pfam; PF13968; DUF4220; 1.
DR   Pfam; PF04578; DUF594; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        38..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        70..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        366..393
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          79..493
FT                   /note="DUF4220"
FT                   /evidence="ECO:0000259|Pfam:PF13968"
FT   REGION          857..914
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        857..896
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   914 AA;  104587 MW;  DCD7EF0C75853AB2 CRC64;
     PLSSYCAQAP LAKRMVSYDD VRDHVASLFI MLNKKTVILF RIEFLVVLAT LLFFAMFLMD
     FFRRMIHNSF MRAVFSVFDA VSDSIVLYLL GAMQTAPFKN QLFPVWALML VNFRYSADYI
     SGYGVPDRRG RRFTEWRNVF KLLGSAFLNW TRGSRFTGPL WSVWCLQIVR SAYRFFSHKL
     AVGSFWHGGS SQLVAEHMRA RYDDSTSNSR VVPDPVTMEG YNYLVYGEES HGFQLKKPMY
     AFSADTSARL PGWFSLARCR CCAAREDTYS STRSSTLVTL DKVWLYFGDT PTQNTDLKDL
     PLAFALSRLL RCRLEDVTLH PCIFKVNREL VKSIIGGKVG ASNALRIMEL QLAFVHDYFN
     TRHPMVFWSG LLSLFVTLVL SMLTIAAVCW LAMDIRRVYK PPNGELANMV KGFNIDMIIT
     WAFILLMIAK EVWEMVTYLL SDWTRLILAC EYVQMRWQGN KFTCLYQMLF SISRRKITDK
     RWHGFIDQYF FMQSYDDRPR LWNFVHNLTT GIIPKKDDGA KLNCAIKVPE FVKKAVLEKL
     STMVEEEQGC SLPRDIKTLS NSNLRKQLQN YKAYSAPPTS TQILLPTSSH IILMWHIATS
     LCEMELVTKH GVNLSNPGFP CSLLSWLTSC CSSKPYLMDL GEKEDDILSW LTNCCSSKSS
     ENLPDELRES YTVANSLSRY CAYLVVAKPD LIPDSFLVPK IVFQKTVQSA RDGILKNCDS
     LESRYKKLKN KAEKPIKDSE KEDVLKQGAV LGKELLNLPT DEARWKILAE VWTELLIHIA
     PTWNAQAHRK CLSGGEFITH IWALLWHYGI QNSSLWPNEV APAAPQNNGV GSENNMDETG
     QACAGISNNQ IEINVHGRDE IKGAQEHETR NSRRGPRRME ETESREIEEG NQDAIVEDTK
     FQRGMAGWPN TKQE
//