ID A0A453SQD3_AEGTS Unreviewed; 937 AA.
AC A0A453SQD3;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Disease resistance protein RPM1 {ECO:0008006|Google:ProtNLM};
OS Aegilops tauschii subsp. strangulata (Goatgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX NCBI_TaxID=200361 {ECO:0000313|EnsemblPlants:AET7Gv21026400.6, ECO:0000313|Proteomes:UP000015105};
RN [1] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=25035499; DOI=10.1126/science.1250092;
RG International Wheat Genome Sequencing Consortium,;
RA Marcussen T., Sandve S.R., Heier L., Spannagl M., Pfeifer M.,
RA Jakobsen K.S., Wulff B.B., Steuernagel B., Mayer K.F., Olsen O.A.;
RT "Ancient hybridizations among the ancestral genomes of bread wheat.";
RL Science 345:1250092-1250092(2014).
RN [2] {ECO:0000313|Proteomes:UP000015105}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. AL8/78 {ECO:0000313|Proteomes:UP000015105};
RX PubMed=29158546; DOI=10.1038/s41477-017-0067-8;
RA Zhao G., Zou C., Li K., Wang K., Li T., Gao L., Zhang X., Wang H., Yang Z.,
RA Liu X., Jiang W., Mao L., Kong X., Jiao Y., Jia J.;
RT "The Aegilops tauschii genome reveals multiple impacts of transposons.";
RL Nat. Plants 3:946-955(2017).
RN [3] {ECO:0000313|EnsemblPlants:AET7Gv21026400.6}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2019) to UniProtKB.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A453SQD3; -.
DR EnsemblPlants; AET7Gv21026400.1; AET7Gv21026400.1; AET7Gv21026400.
DR EnsemblPlants; AET7Gv21026400.6; AET7Gv21026400.6; AET7Gv21026400.
DR Gramene; AET7Gv21026400.1; AET7Gv21026400.1; AET7Gv21026400.
DR Gramene; AET7Gv21026400.6; AET7Gv21026400.6; AET7Gv21026400.
DR Proteomes; UP000015105; Chromosome 7D.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1182; OS09G0270700 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000015105};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..937
FT /note="Disease resistance protein RPM1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5036114419"
FT DOMAIN 20..98
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 181..425
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 937 AA; 107449 MW; 17E8E7BDBE441C72 CRC64;
MADTLFLVLR KIALSLGEAA SEKLSTEVVE AASVLTDFEH GMKQIEGEFM ILQAFIGQVS
TQNVGDRTFD AWLDQVRDVA HQVEDIIDEY NFLTSQAAGI DGFFKRKFRQ AKSFAAWRNL
SSQIDQVETR IQRLTTLKDR YGISVGEPGR SSTLQYARQL SLSDSSYLSD DTELVGNASE
ISMLTQWLLT ERQDRLIMSI LGMGGLGKIT IASSIYKNQQ IIRMFDCHVW VTLSQNYLVE
DLLRQIMKQL MDQRAYMASG IETMSRVRLI EELQSYLQDK KYLIVLDDVW DKDDWLFLKR
ALVINNRGSR VLVTTRKKDV ASLANDGFVV ELKVLPYAEA WHLFCQKAFR RLEDKICPPN
LRPWAEKIVK KCQGLPLAIV AVGSLLSYRE LEEQEWSSLH NQLSWQLANN PELSWIMSVL
NLSLNDLPSH LKNCFLYCSL FPEDYKVKRR WICRLWVAEG LVEERGAGTT MEEVAECYLK
ELTRRSLLEV AERNVHGRAS SFQMHDLVRD ACLIVANREK FAVVYGDSGI TQVNSEVRRL
FVQKHARSLK VAAASRIRSL ILFDTQVASS WIDDISSNFR LIRVLCLRFA NIHQVPAVVP
DLLNLHYLDL AHTKVKHIPA SLGKLTNLQV LDLRFTYVEQ LPWEITNLTK LRHLYVYMLH
DVQERIFDCF SATNIPGNIC RLKNLQSLQS VSANKDLLTQ LGELTLMRSL AIMKMHQNYI
AELWDSLARM PSLSRLVIFA NSKDEVLNLI KIKPLPNLKF FWLRGRLYEG VLPQMFASFE
KLAALKLDCS CLKKDPINSF AHTLNLVYLN LCRAYDGEQL TFRAGWFPKL SSLALVDMEC
LNSIEIEEGA MKVLHTLEIV GLKSLKIVPR GIKHIKTLQK MVLTDMRKEF MDRLHADDSD
IVEHIPDIQS FDSFDSEAGN LHMYTVNTLS KPWLWSV
//
