ID A0A453Z220_ANOME Unreviewed; 1153 AA.
AC A0A453Z220;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Mucin-19 {ECO:0008006|Google:ProtNLM};
OS Anopheles merus (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=30066 {ECO:0000313|EnsemblMetazoa:AMEM019566-PA, ECO:0000313|Proteomes:UP000075903};
RN [1] {ECO:0000313|Proteomes:UP000075903}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MAF {ECO:0000313|Proteomes:UP000075903};
RG The Broad Institute Genomics Platform;
RA Neafsey D.E., Besansky N., Howell P., Walton C., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Anopheles merus MAF (V2).";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:AMEM019566-PA}
RP IDENTIFICATION.
RC STRAIN=MAF {ECO:0000313|EnsemblMetazoa:AMEM019566-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. RGK family.
CC {ECO:0000256|ARBA:ARBA00008846}.
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DR AlphaFoldDB; A0A453Z220; -.
DR STRING; 30066.A0A453Z220; -.
DR EnsemblMetazoa; AMEM019566-RA; AMEM019566-PA; AMEM019566.
DR VEuPathDB; VectorBase:AMEM019566; -.
DR VEuPathDB; VectorBase:AMEM21_009937; -.
DR OrthoDB; 5473132at2759; -.
DR Proteomes; UP000075903; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR021349; DUF2967.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001806; Small_GTPase.
DR PANTHER; PTHR45775; RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C; 1.
DR PANTHER; PTHR45775:SF7; RAD, GEM_KIR FAMILY MEMBER 1, ISOFORM B; 1.
DR Pfam; PF11179; DUF2967; 2.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00173; RAS; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
PE 3: Inferred from homology;
FT REGION 29..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 59..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 161..207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 248..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 316..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 510..558
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 622..653
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 758..799
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 819..855
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1090..1125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..286
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 323..341
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..386
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 526..540
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 622..637
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 763..797
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 830..848
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1153 AA; 122043 MW; 7D3F5CFE536545E0 CRC64;
MTVSVSQPQQ PIESVHCGPL AATYIVASAT PRSSTTSPSS SSASPTTIID AAASPAMALS
TATMSASSSS SSSSTARPTS PGHGRASVSR DSPEPDTTTH GNHSTPTSAL RRLYFKTARA
SKAAKMAATA ATTATAVAAA AASSSTVPKV VVMGSSTTSE ATINTSTDSA STHVTNVTTT
TDTETNDSLD LGDVSGQSEP LLSSLEDESS SIIALSQTAG NEEDENITVI NGPDTPLLIS
YQELEDLSPR SPMFSPRESP KVTPGSNNRT QQPRTAPVSS TATRFPFDPP MSPKTYSGGV
SRGDIASFAR THETMFSFDE SPNPIRRPPP KIPPAPSSAE PDTPDHSPNI PIDTAHGLES
MAAREVTQPP KQQLVEPPQT TTSTPKRLMN SFKTRKERLV QQAGSAVAAA TAAVTSAGGT
SGKPFKNPNY DPDLTMFPFD REAIDYDRIQ RECFAVEEEL LFEHDRRSDD DYRSVSAGAG
CGESPSKALF EAEIFSDHYS IFQQYAYLTQ QETRDGPPAE RNATPSKRNR MATTSSDAFS
PQRRHLEHGS GAGCSSVGSV AASQPRLSKF DQIATKFDLM PSKTGSSCSV TAPQQLGCGT
LPDLRVDYFA ETSCCAGAGI SVSPSGESST CDGKARASSP AATSGGGGGG GLRSMEVVGT
GALAAGAINV TPNPMEGAVC TQPRATIVVQ QPSLSLDYTS VETILLKNEG DFISVGEQGT
KGELQSTQRK KQQREEHMRQ LLDVTNTLTT EEIKDFEMRY GSPHHSRSQS VKTPGSRASG
RPNQLCLPQQ RSRVASMPNT GVEEEYYRLR HFSITGKGVV NRGDSLKSRR SKSNNSVASS
NSSTEHLTPA AGAVAAGSAR TSATCSLASS RESSTSNPAS GPYKVLMLGG PAVGKSSLVS
QFMTSEYLHA YDTSIDDDSG EKTVSVLLSG EESELTFIDH SYSEMAPENC MSTYDPHGYC
VIYSSTDKET FLIAERILQI LWTTENIAQK AVILVANKAD LARCRVVTSD EGKAMATQYD
CKFIETSVGI NHNVDELLVG LLSQIRLKLE NPEKSRDLFR KRSIRKSKRR ACSPLGGAIC
LAGIGGSTNP STPVSGPPAS GGGFVDTPPG SAHSSPRKYR GSRTSASLKV KGLLGRVWAR
DSKSKSCENL HVL
//
