ID A0A455AGE0_PHYMC Unreviewed; 1079 AA.
AC A0A455AGE0;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=E3 ubiquitin-protein ligase PDZRN3 isoform X1 {ECO:0000313|RefSeq:XP_028334559.1, ECO:0000313|RefSeq:XP_028334560.1};
GN Name=PDZRN3 {ECO:0000313|RefSeq:XP_028334559.1,
GN ECO:0000313|RefSeq:XP_028334560.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_028334559.1};
RN [1] {ECO:0000313|RefSeq:XP_028334559.1, ECO:0000313|RefSeq:XP_028334560.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_028334559.1,
RC ECO:0000313|RefSeq:XP_028334560.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_028334559.1; XM_028478758.2.
DR RefSeq; XP_028334560.1; XM_028478759.2.
DR OrthoDB; 2879659at2759; -.
DR Proteomes; UP000248484; Chromosome 18.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00992; PDZ_signaling; 2.
DR Gene3D; 2.30.42.10; -; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR InterPro; IPR001293; Znf_TRAF.
DR PANTHER; PTHR15545:SF5; E3 UBIQUITIN-PROTEIN LIGASE PDZRN3; 1.
DR PANTHER; PTHR15545; PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4; 1.
DR Pfam; PF00595; PDZ; 2.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR SMART; SM00228; PDZ; 2.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 1.
DR PROSITE; PS50106; PDZ; 2.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
DR PROSITE; PS50145; ZF_TRAF; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00207}; Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00207};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00207}.
FT DOMAIN 18..53
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 101..139
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 249..339
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 419..488
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT ZN_FING 101..139
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT REGION 545..602
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 744..869
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 568..586
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 753..774
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1079 AA; 120469 MW; 9A04EE8953AABDB6 CRC64;
MGFELDRFDG DVDPDLKCAL CHKVLEDPLT TPCGHVFCAG CVLPWVVQEG SCPARCRGRL
SAKELNHVLP LKRLILKLDI KCAHAARGCG RVVKLQQLPE HLERCDFAPA RCRHAGCGQV
LLRRDVEAHM RDACDARPVG RCQEGCGLPL THGEQRAGGH CCARALRAHN SALQARLGAL
HKALKKEALR AGKREKSLVA QLAAAQLELQ MTALRYQKKF TEYSARLDSL SRCVATPPGG
KGEETKSLTL VLHRDSGSLG FNIIGGRPCV DNQDGSSSEG IFVSKIVDSG PAAKDGGLQI
HDRIIEVNGK DLSRATHDQA VEAFKTAKEP IVVQVLRRTP RTKMFTPPSE SQTVDTGTQT
DITFEHIMAL TKMSSPTPPV LDPYLLPEEP PSAHEYYDPN DYIEGIHQEM DREELELEEV
DLYRMNSQDK LGLTVCYRTD DEDDIGIYIS EIDPNSIAAK DGRIREGDRI IQINGIEVQN
REEAVALLTS EDNKNFSLLI ARPELQLDEG WMDDDRNDFL DDLHMDMLEV QHHQAMQFTA
GVLQQKKHEE DGGTTDTATI LSNQHEKDSG VGRTDESTRN DESSEQENNG DDAPAASPPL
AGQRKLTCSQ DTLGSGDLPF SNESFISADC ADADYLGIPV DECERFRELL ELKCQVKSAS
PYGLYYPGSP LDASKSDPES VDKELELLNE ELRSIELECL SIVRAHKMQQ LKEQYREPWM
LHNSGFRNYN TSVDVRRREL SDITELPEKS DKDSSSAYNT GESCRSTPLT LEMSPDNSLR
RAAEGVGGPG GSEGAAGTTE AYGPSPRNLL SITEDPEVGS PDYSPSPEEL DPSPALEGKE
GKPGDGSGSP TPSQKLGGGS YLSPFPHSPY KHAHIPAHAQ HYQSYMQLIQ QKSAVEYAQS
QMSLVSMCKD LNSANQSEPR MEWKVKIRSD GTRYITKRPV RDRLLRERAL KIREERSGMT
TDDDAVSELK MGRYWSKEER KQHVVKAKEQ RRRREFMMQS RLDCLKEQQG ADDRKEMNIL
ELSHKKMMKR RNKKIFDNWM TIQELLTHGT KSPDGTRVYN SFLSIRRDRL LRANSENHG
//
