ID   A0A455AH63_PHYMC        Unreviewed;       323 AA.
AC   A0A455AH63;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Lysosomal thioesterase PPT2 isoform X3 {ECO:0000313|RefSeq:XP_028335647.1};
GN   Name=PPT2 {ECO:0000313|RefSeq:XP_028335647.1};
OS   Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Physeteridae; Physeter.
OX   NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_028335647.1};
RN   [1] {ECO:0000313|RefSeq:XP_028335647.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_028335647.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the palmitoyl-protein thioesterase family.
CC       {ECO:0000256|ARBA:ARBA00010758}.
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DR   RefSeq; XP_028335647.1; XM_028479846.2.
DR   AlphaFoldDB; A0A455AH63; -.
DR   STRING; 9755.ENSPCTP00005009199; -.
DR   Proteomes; UP000248484; Chromosome 18.
DR   GO; GO:0098599; F:palmitoyl hydrolase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002472; Palm_thioest.
DR   PANTHER; PTHR11247:SF27; LYSOSOMAL THIOESTERASE PPT2; 1.
DR   PANTHER; PTHR11247; PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1; 1.
DR   Pfam; PF02089; Palm_thioest; 1.
DR   PRINTS; PR00414; PPTHIESTRASE.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..50
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           51..323
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5019774615"
SQ   SEQUENCE   323 AA;  36370 MW;  F0202A1F6FBCCE21 CRC64;
     MDCSIAPPVS GLRCGGHWHG GSMLGLPGLR LPPAGFLFLL PFLLLLPAAP APHRASYKPV
     IVVHGLFDSS YSFRHLLEYI NETHPGTVVT VLDLFDGRES LRPLWEQVQG FREAVAPIMA
     KAPQGVHLIC YSQGGLICRA LLSVMDEHNV DSFISLSSPQ MGQYGDTDYL KWLFPTSMRS
     NLYRICYSPW GQEFSICNYW HDPHHDDLYL NASSFLALIN GERDHPNATA WRKNFLRVGR
     LVLIGGPDDG VITPWQSSFF GFYDANETVL EMEEQLVYLR DSFGLKTLLT RGAIVRCPMA
     EISHTAWHSN RTLYETCIEP WLS
//