ID   A0A455AIB7_PHYMC        Unreviewed;       693 AA.
AC   A0A455AIB7;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=Leucine-rich repeat flightless-interacting protein 2 {ECO:0000256|ARBA:ARBA00040512};
GN   Name=LRRFIP2 {ECO:0000313|RefSeq:XP_028335394.1};
OS   Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Physeteridae; Physeter.
OX   NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_028335394.1};
RN   [1] {ECO:0000313|RefSeq:XP_028335394.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_028335394.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the LRRFIP family.
CC       {ECO:0000256|ARBA:ARBA00008275}.
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DR   RefSeq; XP_028335394.1; XM_028479593.2.
DR   AlphaFoldDB; A0A455AIB7; -.
DR   Proteomes; UP000248484; Chromosome 18.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 1.20.5.4090; -; 1.
DR   InterPro; IPR019139; LRRFIP1/2.
DR   PANTHER; PTHR19212; LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN; 1.
DR   PANTHER; PTHR19212:SF6; LEUCINE-RICH REPEAT FLIGHTLESS-INTERACTING PROTEIN 2; 1.
DR   Pfam; PF09738; LRRFIP; 3.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248484}.
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          49..80
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          92..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          260..310
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          337..496
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          542..569
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          595..685
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        49..66
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        274..310
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   693 AA;  78224 MW;  56DA201B6246EED9 CRC64;
     MGTPGSGRKR TPVKDRFSAE DEALSSIARE AEARLAAKRA ARAEARDIRM RELERQQKEN
     PSKDIMGTHR SRASTPKRKG IMYDAFKDTS SRLSSLNHSY SHSDGMKKRS SGSHKDPLSG
     LYFEQRNYSS LRHSKPTSAY YTRQSSSLYS DPLATSKSYR ASPTANSGLL RSASLASLYD
     GGLYNPYGSR TPSEYSFHSS RTSSTRSSPV FIDDDTASIA SSGRASRGRR ESVVSAADYF
     SRSNRRGSVV SDVDDVSIPD LTSLDEKSDK QYAENYTRPS SRNSASATTP LSGNSSRRGS
     GDTSSLIDPD TSLSELRDIY DLKDQIQDVE GRYMQGLKEL KESLSEVEEK YKKAMVSNAQ
     LDNEKNNLIY QVDTLKDVIE EQEEQMAEFY RENEEKSKEL ERQKHMCSVL QHKMDELKEG
     LRQRDELIEE NQRMQQRIDT MTKEVFELQE TLLWKDKNIR ALEKQKEYIG CLRSERDSLR
     EELAELKAAV ETGEKHGLVI IPDGTPNGDV HQEPVVGAIA VVSQEAAQVL ESAGEGPLDV
     RLRKLAGEKE ELLSQIRKLK LQLEEERQKC SRSDGTAGDL AGLQNGSDLQ LIEMQRDANR
     QISEYKFKLS KAEQDITTLE QSISRLEGQV LRYKTAAENA EKVEDELKAE KRKLQRELRT
     ALDKIEEMEM TNSHLAKRLE KMKANRTALL AQQ
//