ID A0A455ANP9_PHYMC Unreviewed; 730 AA.
AC A0A455ANP9;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Nuclear body protein SP140-like protein isoform X8 {ECO:0000313|RefSeq:XP_028338295.1};
GN Name=LOC102975826 {ECO:0000313|RefSeq:XP_028338295.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_028338295.1};
RN [1] {ECO:0000313|RefSeq:XP_028338295.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_028338295.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_028338295.1; XM_028482494.2.
DR AlphaFoldDB; A0A455ANP9; -.
DR Proteomes; UP000248484; Chromosome 2.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd05501; Bromo_SP100C_like; 1.
DR CDD; cd15626; PHD_SP110_140; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.10.390.10; SAND domain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR004865; HSR_dom.
DR InterPro; IPR010919; SAND-like_dom_sf.
DR InterPro; IPR000770; SAND_dom.
DR InterPro; IPR043563; Sp110/Sp140/Sp140L-like.
DR InterPro; IPR030411; Sp140_Bromo.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46386; NUCLEAR BODY PROTEIN SP140; 1.
DR PANTHER; PTHR46386:SF8; NUCLEAR BODY PROTEIN SP140; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF03172; HSR; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF01342; SAND; 1.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00258; SAND; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF63763; SAND domain-like; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS51414; HSR; 1.
DR PROSITE; PS50864; SAND; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 49..165
FT /note="HSR"
FT /evidence="ECO:0000259|PROSITE:PS51414"
FT DOMAIN 439..520
FT /note="SAND"
FT /evidence="ECO:0000259|PROSITE:PS50864"
FT DOMAIN 550..596
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 631..689
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 274..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 324..438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..375
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 84217 MW; 638DD94AEC88AFEC CRC64;
MQLGGHCWNS LVSLGLATRL DDSLCPLSRP ISPVTSLIPY LQRQVCRMIA GDQNPEEQNP
EEQFFYEFIF RLFKENKVEI ASAVTKPFPF LMGLRDRGFI PEQMYEHFQE ACGNLVPVER
VVYDALNELE KKFDKTVLDA LFSRVNLKAY PDLLQICRNF QNVIHENFYY QTIGEGETKE
TLNLQLNHEQ VSLEQSPLQM NNVIRLEDVP SLLPYDRQGN NSACWETCFG EEPQGALNFP
PRCELVTCYP KAPQLTHEEE PKQVLSLLPG EGEVSCDPEA SQMTNKEVPE ELPSQPLCDG
EGAELPTFGN EKCSCVMCFS KDVPGGPEGS TESKEASDKM DTVDLGNNST LGKLKRKRKK
RKGHSWTRVK MKLQRNKHQK DNSNADGQLA SSGKKVKMNL QDPAKIRRRK RGRQRLHLTH
SDRAPWKKVK SRGQRKCRHE KVDFHSQILP VTCGKVKGML HKKKLKEGVW VKCIRSENGG
WFTPREFEIR GGHERSKNWK ISVRCGGMPL RWLIEKRFLH NPPRKYGKIR KKRVPKSHDN
TLDNLCLGNS DVCETCRDGG KLFCCDTCSR SFHEDCHIPP VETERSLWSC TFCRIKESSG
SQRCLGESEV LARQMQPEEQ LKCEFLLLKV YCHSESTFFA KIPYYYYIKE ASKNLKEPMW
LDKIKKRLNE QGYSHVEGFV QDMRLIFQNH RASYKFNDFG LMGLRLEAEF EKNFKEVFTI
QETNEDSSLE
//
