ID   A0A455B3Q7_PHYMC        Unreviewed;       279 AA.
AC   A0A455B3Q7;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Complement component C8 gamma chain isoform X5 {ECO:0000313|RefSeq:XP_028342708.1};
GN   Name=C8G {ECO:0000313|RefSeq:XP_028342708.1};
OS   Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Physeteridae; Physeter.
OX   NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_028342708.1};
RN   [1] {ECO:0000313|RefSeq:XP_028342708.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_028342708.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the calycin superfamily. Lipocalin family.
CC       {ECO:0000256|RuleBase:RU003695}.
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DR   RefSeq; XP_028342708.1; XM_028486907.2.
DR   AlphaFoldDB; A0A455B3Q7; -.
DR   STRING; 9755.ENSPCTP00005019191; -.
DR   KEGG; pcad:114485457; -.
DR   Proteomes; UP000248484; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005579; C:membrane attack complex; IEA:InterPro.
DR   GO; GO:0006956; P:complement activation; IEA:InterPro.
DR   Gene3D; 2.40.128.20; -; 1.
DR   InterPro; IPR002968; A1-microglobln.
DR   InterPro; IPR043245; C8G.
DR   InterPro; IPR012674; Calycin.
DR   InterPro; IPR022272; Lipocalin_CS.
DR   InterPro; IPR000566; Lipocln_cytosolic_FA-bd_dom.
DR   PANTHER; PTHR47304; COMPLEMENT COMPONENT C8 GAMMA CHAIN; 1.
DR   PANTHER; PTHR47304:SF1; COMPLEMENT COMPONENT C8 GAMMA CHAIN; 1.
DR   Pfam; PF00061; Lipocalin; 1.
DR   PRINTS; PR01215; A1MCGLOBULIN.
DR   SUPFAM; SSF50814; Lipocalins; 1.
DR   PROSITE; PS00213; LIPOCALIN; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..279
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5019716725"
FT   DOMAIN          48..183
FT                   /note="Lipocalin/cytosolic fatty-acid binding"
FT                   /evidence="ECO:0000259|Pfam:PF00061"
FT   REGION          254..279
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   279 AA;  30412 MW;  435465179A4EBF0C CRC64;
     MLTPRTASLL TLLLAVGSLG QRAQRPPRPP SPISTVQPKA NFDAQQFSGT WFLVAVASSC
     RSLQEQGHRA EATTLHVTPQ GAAMAVSTFR KLDGICWQVR QLYRDTGLPG RFLLQARGAR
     GAVDVVVGET DYRGFAILYL ERARQLSVKL YARSLPVSES FLSVFEQRVQ GANLTEDHTL
     FFPKYGFCEA ADQFHVLDGE RAAPAGRCGR GLAARGSLLV ESRLCCRSEE VRPAAALHRE
     AAKALEEAAP ATPLAEWGTL SRPPPKPHLT PRSSGRCLH
//