ID   A0A455B3S6_PHYMC        Unreviewed;       696 AA.
AC   A0A455B3S6;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Exostosin-like 1 isoform X2 {ECO:0000313|RefSeq:XP_028343422.1};
GN   Name=EXTL1 {ECO:0000313|RefSeq:XP_028343422.1};
OS   Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Physeteridae; Physeter.
OX   NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_028343422.1};
RN   [1] {ECO:0000313|RefSeq:XP_028343422.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_028343422.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004648}; Single-pass type II membrane protein
CC       {ECO:0000256|ARBA:ARBA00004648}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 47 family.
CC       {ECO:0000256|ARBA:ARBA00010271}.
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DR   RefSeq; XP_028343422.1; XM_028487621.2.
DR   AlphaFoldDB; A0A455B3S6; -.
DR   Proteomes; UP000248484; Chromosome 3.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR   GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR   InterPro; IPR004263; Exostosin.
DR   InterPro; IPR040911; Exostosin_GT47.
DR   InterPro; IPR015338; GT64.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR48261; ACETYLGLUCOSAMINYLTRANSFERASE; 1.
DR   PANTHER; PTHR48261:SF2; EXOSTOSIN-1-LIKE; 1.
DR   Pfam; PF03016; Exostosin; 1.
DR   Pfam; PF09258; Glyco_transf_64; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          105..325
FT                   /note="Exostosin GT47"
FT                   /evidence="ECO:0000259|Pfam:PF03016"
FT   DOMAIN          376..618
FT                   /note="Glycosyl transferase 64"
FT                   /evidence="ECO:0000259|Pfam:PF09258"
SQ   SEQUENCE   696 AA;  76290 MW;  E150F30DDAC2426D CRC64;
     MQSWRWKSLW LALLASWLLV LLGVFPLLRL AVPTRPRAGV PQGWPHWLDA ELLQSFAKPG
     ELLEDGPQPP QALRGGSCNW GACFDTSKCR GGGLKVFVYP AAGPVSETHR RILASIEGSR
     YHTLSAAEAC LLLLLSPDTP TGECDPVPPQ WDGGRNHLVL SLHPAPCPRT FQLGQAMVAG
     ASPTVDTFRP GFDVALPLLP EAHPLRGGVP GQLRQHSPRP GVALLALAED RGRWHVAGTD
     FSACPWDGRC EQDRGPKQTH PGATLPNATF CLIPGRSPDA LHFLQALQAG CIPVLLSPRW
     QLPFSEVIDW TKAAIVADER LPLQIIQDRI FGASAHPSLL WNSPPGAILA LPTFSPSPSD
     FPFYHLQQGS RPLGRFSALI WGGAPGQPPL KLIQAVAGSQ HCAQILVLWS SEKPPPTRWP
     KTAVPLTVID GHRKVSDRFF PYSAISTDAI LSLDAHSSLS TSEVDFAFVV WQSFPERMVG
     FLTWSHFWDE ARGGWGYTAK RTNEFSMVLT SAAFYHRYYH TLFTHSLPKA LRTLADEAPT
     CVDVLMNFLV ASVTKLPPIK VPYGMWHQEA RPPPLEPGGP GLTQEPQPAA HNCINQMAAG
     FGHMPLVSSR LRLDPVLFKD PVSVLRKKSS PPPRTCLTPT PAPDPLRFHS RMCPLVPTLF
     MLPRKVHRQG PGLTREPREG RAVSSSLWPG RCATNI
//