ID A0A455B7X0_PHYMC Unreviewed; 2280 AA.
AC A0A455B7X0;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Myomegalin isoform X18 {ECO:0000313|RefSeq:XP_028344739.1};
GN Name=PDE4DIP {ECO:0000313|RefSeq:XP_028344739.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_028344739.1};
RN [1] {ECO:0000313|RefSeq:XP_028344739.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_028344739.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_028344739.1; XM_028488938.2.
DR Proteomes; UP000248484; Chromosome 4.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0005815; C:microtubule organizing center; IEA:InterPro.
DR InterPro; IPR012943; Cnn_1N.
DR InterPro; IPR010630; Olduvai_dom.
DR PANTHER; PTHR46501; MYOMEGALIN; 1.
DR PANTHER; PTHR46501:SF2; MYOMEGALIN; 1.
DR Pfam; PF07989; Cnn_1N; 1.
DR Pfam; PF06758; Olduvai; 1.
DR SMART; SM01148; DUF1220; 1.
DR PROSITE; PS51316; ODV; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484}.
FT DOMAIN 1552..1643
FT /note="Olduvai"
FT /evidence="ECO:0000259|PROSITE:PS51316"
FT REGION 220..241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 704..742
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1592..1621
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1634..1694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1820..1839
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 41..122
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 168..205
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 241..303
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 355..424
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 580..633
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 749..884
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1000..1041
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1352..1386
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1898..2020
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 704..736
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1592..1618
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1643..1694
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1821..1839
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2280 AA; 257148 MW; 5E04E238DC6CCED5 CRC64;
MSNGYRTLSQ HLNDLKKENF SLKLRIYFLE ERMQQKYEAS REDIYKRNIE LKVEVESLKR
ELQDKKQHLD KTCTDVENLN SHNEAELRRQ FEERQQETEH VYELLENKIQ LLQEESRLAK
NEAARMAALV EAEKECNLEL SEKLKGVTKD REDVPGNRVK PNQYTEALAQ RDKRIEELSQ
SLAAQEKLAE QLSQEKQQLL HLLEEPADME VQPTTEELLR QPKLNSGETS TTQQAVSDSH
LTELQEKIQQ TEATNKILQE KLNEMSCELK SAQESSQKQD GTIQNLKETL KSRENETEEL
YQVIEGQNDT MVKLREMLHQ SQLGQLHNSE GTSPAQQQVA LLDLQSALFC SQLEIQKLQR
VVRQKERQLA DARRCVQFVE AAAQEREQQK EASWKHNQEL RKALQQLQGE LQSKGQQLHT
LEAEKYNEIR TQEQHIQHLN HSLSHKEQLL QEFRELLQYR NNSDKTLEAN EMLLEKLRQR
IQDRDVALER AIDEKFSSLE EKEKELRQLC LAVRERDHDL ERLRGILSSN EATMQCMESL
LRAKGLEVEQ LSASCQNVQW LKEEMETKFS HWQKEQESII QQLQTSLHDR NKEVEDLSAT
LLCKLGPGQS EIAEELCQRL QRKERILQDL LSDRNKQAVE YEMEIQGLLH SMSSREQESQ
AAAEKMVQAL MERNSELQAL RQYLGGKDFM MSQALISNQP AEVTSVSRHL GEQTDQGSVP
IPSRDDSTSL TDKGDTSIPR SALGDLDTVA GLEKELSNAK EELELMAKKE RESRMELSAL
QSMMAVQEEE LQVQAADMES LTRTIQIKED LIKDLQMQLV DPEDIPAMER LTQEVLLLRE
KVASVESQGQ ETSGNRRQQL LLMLEGLVDE RSRLNEALQA ERQLYSSLVK FHAHPESSER
DRTLQVELEG AQVIRSRLEE VLGRSLERLS RLETLAAIGG AAAGDDTEDA STEFTDSIEE
EAAHNSHQQL IKVALEKSLA AVETQNVSLA PPSTTGGDSN RGLQEEMLHL RAEIHQLLEE
KRKAEGELKE LKAQIEEAGF SSVAHIRNTM LSLCLENAEL KEQMGEAMSD GWEIEEDKEK
GEVMVETVVA KGGLNENSLQ AEFRKLQGKL KNAHNIINLL KEQLVLSTRE GNSKLNPELL
GHLSREIDRM NTELVCSSGK HQCQEEEGVT MRPCPRPQSL DLGTAFTADT HQLVNQPQAR
NSGPQSEFSL PGSTKHLRSQ LAQCRQHYQD LQEKLLISEA TVFAQANQLE KYRVMFTGES
LVKQDSKQVQ VDLQDLGYET CGRSENEAER EESTSPECEE HDSLRETVLM EGLCSEQGHL
GSTLASPCGK KSLESQLGKQ EEFQAYGKSE DISVLCKDIK DLKAQLQNAN KVIQNLKSRV
RSLSVTSDYS SSLERPQKLK AVGTLEGSSP HSVTDEDEGW LSDGTGAFYP PGLQAKKDLE
SLIQRVSQLE AQLPKTGTEG KLAEELRSAS WPGKYDSLIQ DQARELSYLR QKIREGRGIC
YLLTQHAKDT VKSFEDLLRS NDIDYYLGQS FREQLAQGSQ LTERLTSKLS TKDHKSEKDQ
AGLEPLALRL SRELQEKEKV IEVLQATLDA RSLTPSSSRA LSDSHRSPSS SSFSSDEPEA
CSDMDIASEY THYEEKKASP GHSDSICHSS HSAVLSSKPS ATSASQGVKA EPSSSPISLP
APQSPHKEAS QAHSGLHFQS IPTLVSLPQA PLPSAPPSFL PFSSAGPPLL GCCETPMVSL
AEAQQELQML QKQLGESVSN VHPASPATLP TNHLEASSSH YLNPAQPLSP LRGTIELGRI
LKPGYLGSRG QWDMMRPQKG SISGDLSSGS STYQLNSKPT GTDLLEEHLG EIRSLRQRLE
ESICINERLR EQLEHRLSST ARGSGPTSNF YSPGLESTSQ LCNENRVLRE ENQRLQAQLN
HASREHSQET ECLREALLTS RSQLQELEME REHQKVERQQ LLEDLKEKQQ EILHFEEERL
SLQEKDSRLQ HKLALLQHQC EEKQQLFQSL QSELQIYEAL YGNSKKGLKE LGLDASPVMK
NPPKLEGDAT DGSFANKHGR HVIGHIDDYS ALRQQIGEGR LLVKKIASLM RSTCNFPGLE
APGTEVMGSE GIHELRNSAN ALHHRLEESA SLLTMFWRAA LPSSHGPALD SKAGECMKRE
LLELRTKLSK QESLLRSTAE HLKAANQQKE SMEQFIFSQL SRTHDVLKKA RTNLEKNTYK
IASVKPYSCL SKGEIPKGSA MHSSPVTLAF QEPSKKRSHQ RSLKQQEGWA CPPSLQLPVC
//
