ID   A0A455B9W9_PHYMC        Unreviewed;       435 AA.
AC   A0A455B9W9;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Ganglioside-induced differentiation-associated protein 2 isoform X3 {ECO:0000313|RefSeq:XP_028344758.1};
GN   Name=GDAP2 {ECO:0000313|RefSeq:XP_028344758.1};
OS   Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Physeteridae; Physeter.
OX   NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_028344758.1};
RN   [1] {ECO:0000313|RefSeq:XP_028344758.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_028344758.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the GDAP2 family.
CC       {ECO:0000256|ARBA:ARBA00008355}.
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DR   RefSeq; XP_028344758.1; XM_028488957.2.
DR   AlphaFoldDB; A0A455B9W9; -.
DR   Proteomes; UP000248484; Chromosome 4.
DR   CDD; cd02905; Macro_GDAP2-like; 1.
DR   CDD; cd00170; SEC14; 1.
DR   Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR   Gene3D; 3.40.220.10; Leucine Aminopeptidase, subunit E, domain 1; 1.
DR   InterPro; IPR001251; CRAL-TRIO_dom.
DR   InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR   InterPro; IPR002589; Macro_dom.
DR   InterPro; IPR043472; Macro_dom-like.
DR   InterPro; IPR035793; Macro_GDAP2.
DR   PANTHER; PTHR11106; GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED; 1.
DR   PANTHER; PTHR11106:SF72; GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 2; 1.
DR   Pfam; PF13716; CRAL_TRIO_2; 1.
DR   Pfam; PF01661; Macro; 1.
DR   SMART; SM00506; A1pp; 1.
DR   SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR   SUPFAM; SSF52949; Macro domain-like; 1.
DR   PROSITE; PS51154; MACRO; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000248484}.
FT   DOMAIN          43..223
FT                   /note="Macro"
FT                   /evidence="ECO:0000259|PROSITE:PS51154"
FT   REGION          254..273
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   435 AA;  49156 MW;  DB8F460FB9F0280F CRC64;
     MDPLGAPSQF VDVDTLPSWG NSCEEQLTTS DTAAETYQEE TIRSPFLYNK DINGKVVLWK
     GDVALLNCTA IVNTSNESLT DKNPVSESIF MLAGPDLKED LQKLRGCRTG EAKLTKGFNL
     AARFIIHTVG PKYKSRYRTA AESSLYSCYR NVLQLAKEQS MSSVGFCVIN SAKRGYPLED
     ATHIALRTVR RFLEIHGETI EKVVFAVSEL EEATYQKLLP LYFPRSLKEE SCSLPYLPAD
     IGNAEGEPVV PERQIRISEK PGAPEDNQEE EDEGLGVDLS FIGSHAFARM EGDIDKQRRL
     ILQGQLSEAA LQKQHQRNYN RWLCQARSED LSDIASLKAL YQTGVDNCGR TVMVVVGRNI
     PVTLIDMDKA LLYFIHVMDH IAVKEYVLVY FHTLTSEYNH LDSDFLKKLY DVVDVKYKRN
     LKAVYFVHPT FRSKD
//