ID   A0A455BAH5_PHYMC        Unreviewed;       314 AA.
AC   A0A455BAH5;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   08-NOV-2023, sequence version 2.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Endonuclease/exonuclease/phosphatase family domain-containing protein 1 isoform X5 {ECO:0000313|RefSeq:XP_028345694.2};
GN   Name=EEPD1 {ECO:0000313|RefSeq:XP_028345694.2};
OS   Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Physeteridae; Physeter.
OX   NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_028345694.2};
RN   [1] {ECO:0000313|RefSeq:XP_028345694.2}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_028345694.2};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_028345694.2; XM_028489893.2.
DR   KEGG; pcad:114486295; -.
DR   OrthoDB; 3037349at2759; -.
DR   Proteomes; UP000248484; Chromosome 5.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   Gene3D; 1.10.150.280; AF1531-like domain; 1.
DR   Gene3D; 1.10.150.320; Photosystem II 12 kDa extrinsic protein; 1.
DR   InterPro; IPR004509; Competence_ComEA_HhH.
DR   InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR   InterPro; IPR010994; RuvA_2-like.
DR   NCBIfam; TIGR00426; competence protein ComEA helix-hairpin-helix repeat region; 1.
DR   PANTHER; PTHR21180; ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR21180:SF32; ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF12836; HHH_3; 2.
DR   SMART; SM00278; HhH1; 3.
DR   SUPFAM; SSF47781; RuvA domain 2-like; 2.
PE   4: Predicted;
KW   Endonuclease {ECO:0000313|RefSeq:XP_028345694.2};
KW   Hydrolase {ECO:0000313|RefSeq:XP_028345694.2};
KW   Nuclease {ECO:0000313|RefSeq:XP_028345694.2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248484}.
FT   DOMAIN          48..67
FT                   /note="Helix-hairpin-helix DNA-binding motif class 1"
FT                   /evidence="ECO:0000259|SMART:SM00278"
FT   DOMAIN          78..97
FT                   /note="Helix-hairpin-helix DNA-binding motif class 1"
FT                   /evidence="ECO:0000259|SMART:SM00278"
FT   DOMAIN          145..164
FT                   /note="Helix-hairpin-helix DNA-binding motif class 1"
FT                   /evidence="ECO:0000259|SMART:SM00278"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          200..226
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   314 AA;  34322 MW;  07D543EC86287CE9 CRC64;
     MGSTLGCHRS IPRDPSDLSH SRKFSAACNF SNILVNQERL NINTATEEEL MTLPGVTRAV
     ARSIVEYREY IGGFKKVEDL ALVSGVGATK LEQVKFEICV SSKGSSAQHS PSSLRRDLLA
     EQQPHHLATA VPLTPRVNIN TATPAQLMSV RGLTEKMAVS IVDYRREHGP FRSVEDLVRM
     GGVNAAFLDR IRHQVFAERS RPPSTHTNGG LTFTAKPHPS PTSLSLQSED LDLPPGGPTQ
     IISTRPSVEA FGGTRDGRPV LRLATWNLQG CSVEKANNPG VREVVCMTLL ENSIKLLAVQ
     ELLDREALEK TFPL
//