ID   A0A455BPR1_PHYMC        Unreviewed;      1628 AA.
AC   A0A455BPR1;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=LOW QUALITY PROTEIN: NACHT domain- and WD repeat-containing protein 1 {ECO:0000313|RefSeq:XP_028350934.1};
GN   Name=NWD1 {ECO:0000313|RefSeq:XP_028350934.1};
OS   Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Physeteridae; Physeter.
OX   NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_028350934.1};
RN   [1] {ECO:0000313|RefSeq:XP_028350934.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_028350934.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_028350934.1; XM_028495133.1.
DR   STRING; 9755.ENSPCTP00005011250; -.
DR   KEGG; pcad:102988189; -.
DR   InParanoid; A0A455BPR1; -.
DR   OrthoDB; 2910252at2759; -.
DR   Proteomes; UP000248484; Chromosome 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR043365; NWD1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR45013; NACHT DOMAIN- AND WD REPEAT-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR45013:SF1; NACHT DOMAIN- AND WD REPEAT-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF00400; WD40; 4.
DR   SMART; SM00320; WD40; 8.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF69322; Tricorn protease domain 2; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 4.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   DOMAIN          337..505
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|Pfam:PF05729"
FT   REPEAT          932..973
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          974..1015
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          1181..1222
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          1448..1482
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ   SEQUENCE   1628 AA;  180559 MW;  81B776308D35CDDF CRC64;
     MQRGKPYRAP PTXIVQTFCX KHGLMSEVIA RLWRIQNTEA TNHMTTELCL EELGWCQKTS
     IGPAFVALVG DHYGPRPVPS LIEEKEWEAL KAQLSARPRD LELVARRFRT DENAVPPTYL
     LQTLGSGEAR GPEEATLTSA LRSGAQEARR LGLITQEKWH CYHRSVIEGE IERGLLSSTD
     WDQGATVFLR DIQDLNKHIL EVCDLKMVEL LAAGCLDKDA QNLLSSLKER ITDMQPGVLK
     AHHLAWSRDL VDPPNKAHGR YPKELGEQFV ARANHQVLKC LQKLEAGRRE LARLYQEIRH
     HLGLSAEAPR TFCGRQELLT QLGQQLQQSD GHPHPPLVLF GPPGIGKTAL MCKLAEQMPG
     LLGHKTVTVL RLLGTSQMSS DARGLLQSIC FQVRLAYGLP LPPAQVLEAH TRVVQFFHTL
     LHTVSCQNFE SLVILLDLVD EVDSVHRARR VPWLPPKCPP RVHLILSVCS GXAGVLDTMR
     QLLTDPGAYW EVKPLSGNQG QEMVQLLLAA SRRTLSLMQR DLLWASLPEC GHPGRLRLAF
     EEARKWASFT VPAPLASTAK EAMHQLCALL EQTHGQLLVA RVLGYIVSSR HGLSEAEMKD
     ALSLDDEVLQ AMYQDWTPPS KELPRFPPLL RVRLRRDLGN CLARRPVDGC ILLVIAHRQL
     AEVVRERYLS WPEKAKGHRV LADFFSGTWS QGTKKLITLP LVGKPLNLNH RQLAEVVRER
     YLSWPEKAKG HRVLADFFSG TWSQGTKKLI TLPLVGKPLN LNHRCPAPHL EPPSRCTCKV
     VPQPLWFSDT VANLQKLKEL PYHLIHSGCI EELKQEVLGS MNWISCRGIS GGIEGLLDDX
     DLCAPHVDCP EVSLVREALQ LCCPAVELRG MERSILYTEL LARLYFFATS HPVLVGQLCQ
     QAQSWFWMCP HPVLVPLRRF LQPPGGTLQA TLIGCHKDIT AMAWRLEEKL LVVGIQEGMV
     AVWDMEEQQV IHILPGHTGE VRCVKVFVKG SLAISTSKDH TLCLWNLLSG QEKFTIWDGG
     SKDPTEPQIS SLHVDEAKKV VYSASSSKVN AWNLETEELI FRTLGDASDP GVCTAVLASR
     VTLLTVSQGG VVSLWSSATG TLQRKQHLSS IKEETITCGV SVQKQRKMVT RSSKGSISLV
     SNLTEXDANI NSAPKCSDGF GRSMRIFLSD LQGFHQFMVT DLEHEDMVKT AIFGPENNLI
     VTGSRDELIQ VWSLSEQGSL LDVLEDVGAP VSLLARGGPL VASASHQSSS FNVWDLTYAQ
     KPRASTPFLD CTGLTAVSHN GSYVYFPKIG DKNKVTIWDL AEGFLLPMAC KEQGALDTSN
     EVRWLEAAEQ GNLLFTGLVS GIILVFPLNS RQDVMCIPPP EARKAINCMA LSKDEGHLAI
     AYDNIVLVLD ISPGDPCPVI DRPTYTFYTQ LPDTIASVAV LADYRIICGM TNGDLFLYEC
     ANSKVFPLEA HGSRVTCVEV SHKEQLAVSG SEEALLCLWD LQACKWKFEM SYTNSCCRGV
     QCACFSKDDK YVYAGLKDSS IIVWSVLDGT LLAIQFVHAV VNRIIPASNG FIAPTRHGYL
     IRERFQCPSS RISQQGPLKN FKKAVWVVKS RQREELAAAA GALQDSRSGS AQGNXSKSNK
     CSQVCLLV
//