ID   A0A455BQ26_PHYMC        Unreviewed;      1240 AA.
AC   A0A455BQ26;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=LOW QUALITY PROTEIN: transient receptor potential cation channel subfamily M member 1 {ECO:0000313|RefSeq:XP_028351085.1};
GN   Name=TRPM1 {ECO:0000313|RefSeq:XP_028351085.1};
OS   Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Physeteridae; Physeter.
OX   NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_028351085.1};
RN   [1] {ECO:0000313|RefSeq:XP_028351085.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_028351085.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   RefSeq; XP_028351085.1; XM_028495284.2.
DR   STRING; 9755.ENSPCTP00005027720; -.
DR   KEGG; pcad:102983635; -.
DR   InParanoid; A0A455BQ26; -.
DR   OrthoDB; 201873at2759; -.
DR   Proteomes; UP000248484; Chromosome 11.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR041491; TRPM_SLOG.
DR   PANTHER; PTHR13800:SF13; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 1; 1.
DR   PANTHER; PTHR13800; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF18139; LSDAT_euk; 1.
PE   4: Predicted;
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|RefSeq:XP_028351085.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00023303}.
FT   TRANSMEM        867..886
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        934..952
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1002..1023
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1079..1104
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          107..372
FT                   /note="TRPM SLOG"
FT                   /evidence="ECO:0000259|Pfam:PF18139"
FT   DOMAIN          873..1113
FT                   /note="Ion transport"
FT                   /evidence="ECO:0000259|Pfam:PF00520"
FT   REGION          440..480
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          609..631
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          812..845
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1240 AA;  141884 MW;  43926F01A375AD09 CRC64;
     MAWEYLGLIS TFFXFQGQKS WIEKTFCKRE CIFVIPSTKD PNRCCCGQLT NQHIPPLPSV
     TASKNGEENK QVETQPEKWS VGKHTQSYPT DSYGILEFQG GGYSNKAMYI RVSYDTKPDS
     LLHLMVRDWQ LELPKLLISV HGGLQNFEMQ PKLKQVFGKG LIKAAVTTGA WIFTGGVSTG
     VISHVGDALK DHSSKSRGRV CAIGIAPWGI VENKEDLVGR DVTRVYQTMS NPLSKLSVLN
     NSHTHFILAD NGTLGKYGAE VMLRRQLEKH ISLQKINTRL GQGVPVVGLV VEGGPNVVSM
     VLEYLREEPP VPVVVCDGSG RASDILSFAH KYSEEGGVIN DSLRDQLLVT IQKTFNYNKT
     QSHQLFVMIM ECMKKKELVT VFRMGSEGQQ DIEMAILTAL LKGTNASARD QLSLALAWNR
     VDIARSQIFV FGPRWPPLGS LAPPTDSKAM EKKKPPTATT KGGRGKGKGK KKGKVKEEVE
     EETDPRKLEL LNWVNALEQA MLDALVLDRV DFVKLLIENG VNMQHFLTIP RLEELYNTRL
     GPPNTLHLLV RDVKKGNLPP DYHISLIDIG LVLEYLMGGA YRCNYTRKGF RTLYNNLFGP
     KRPKALKLLG MEDDEPPAKG KKKKKKKKEE ELDIDVDDPA VSRFQYPFHE LMVWAVLMKR
     QKMAVFLWQR GEESMAKALV ACKLYKSMAH ESSESELVDD ISQDLDNNSK DFGQLAVELL
     DQSYKHDEQI AMKLLTYELK NWSNSTCLKL AVAAKHRDFI AHTCSQMLLT DMWMGRLRMR
     KNPGLKVIMG ILLPPTILFL EFRTCDDFSY QTSKENEDGK EKEEENVDAN ADPGSRKGDE
     ENEQKKQRSV PIGTKICEFY NAPIVKFWFY TISYLGYLLL FNYVILVRME RWPCLQEWIV
     ISYIVSLALE KIREILMSEP GKLSQKIKVW LQEYWNITDL VAISMFMIGA ILRLQKQPYM
     GYGRVIYCVD IIFWYIRVLD IFGVNKYLGP YVMMIGKMMI DMLYFVVIML VVLMSFGVAR
     QAILHPDEEP SWKLARNIFY MPYWMIYGEV FADQIDPPCG DNQYDEEGKR LPPCIPGAWL
     TPAIMACYLL VANILLVNLL IAVFNNTFFE VKSISNQVWK FQRYQLIMTF HDRPVLPPPM
     IILSHVYIII MRLSRHCRKK REGDQDEQDR GLKLFLSDEE LKRLHEFEEQ CVREHFQEKE
     DEQQSSSEER IRVTCERCAW GMTTAGRGAQ SQRVRLLRPV
//