ID A0A455BYH6_PHYMC Unreviewed; 612 AA.
AC A0A455BYH6;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Zinc finger protein 354B isoform X1 {ECO:0000313|RefSeq:XP_028354090.1, ECO:0000313|RefSeq:XP_028354093.1};
GN Name=LOC114483920 {ECO:0000313|RefSeq:XP_028354090.1,
GN ECO:0000313|RefSeq:XP_028354093.1, ECO:0000313|RefSeq:XP_028354099.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_028354099.1};
RN [1] {ECO:0000313|RefSeq:XP_028354090.1, ECO:0000313|RefSeq:XP_028354093.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_028354090.1,
RC ECO:0000313|RefSeq:XP_028354093.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_007120599.1; XM_007120537.1.
DR RefSeq; XP_007120600.1; XM_007120538.1.
DR RefSeq; XP_007120601.1; XM_007120539.1.
DR RefSeq; XP_007120602.1; XM_007120540.1.
DR RefSeq; XP_028354090.1; XM_028498289.2.
DR RefSeq; XP_028354093.1; XM_028498292.2.
DR RefSeq; XP_028354099.1; XM_028498298.2.
DR STRING; 9755.ENSPCTP00005002271; -.
DR Ensembl; ENSPCTT00005002497; ENSPCTP00005002271; ENSPCTG00005001661.
DR KEGG; pcad:114483920; -.
DR OrthoDB; 4710209at2759; -.
DR Proteomes; UP000248484; Chromosome 2.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 13.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24379; KRAB AND ZINC FINGER DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR24379:SF116; ZINC FINGER PROTEIN 672; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 13.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 13.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 8.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 13.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 13.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 14..85
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 215..242
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 243..270
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 271..298
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 299..326
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 355..382
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 383..410
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 411..438
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 439..466
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 467..494
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 495..522
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 523..550
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 551..578
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 579..606
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 73..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 612 AA; 70172 MW; C3458FBC7BB29FF5 CRC64;
MATEQREARS QLSVTFEDVA VLFTRDEWRK LAPSQRNLYQ DVMLENYSNL VSLGLPFSKP
EVISLLQQGE DPWKVEKESP GGSSVGCKSS PKTTKSTQTQ DSSFWGPVRK RLKKNEPWNF
ISEKPCIYED RIKKQKDKNG SLQIISVTHT KILTVERSHK NNDFGQNFSL KSVFVKQQKI
AREKTPSKYE MQRNSFRQDS NLLNQPKTKT AEKRYKCNTC EKAFIHNSSL RKHQKNHTGE
KLFKCKECLK AFSQSSALIQ HQRTHTGEKP YICKECGKAF SHSASLCKHL RTHTVEKSYR
CKECGKSFSR RSTLFIHQKI HARENPHKYN PGRKASSCST SPSGCQKIHL RKKSYLCNEC
GNTFKSSSSL RYHQRIHTGE KPFKCSECGR AFSQSASLIQ HERIHTGEKP YRCNECGKGF
TSISRLNRHR IIHTGEKLYN CNECGKALSS HSTLIIHERI HTGEKPCKCK VCGKAFRQSS
ALIQHQRMHT GERPYKCNEC GKTFRCNSSL SNHQRIHTGE KPYQCLECGI SFGQSAALIQ
HQRIHTGEKP FACNTCGKTF RQSSSLIAHQ RIHTGEKPYE CNACGKLFSQ RSSLTNHYKI
HIEENFKVDL HV
//
