ID A0A455C1E5_PHYMC Unreviewed; 210 AA.
AC A0A455C1E5;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 08-NOV-2023, sequence version 2.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Protein tweety homolog {ECO:0000256|RuleBase:RU361114};
GN Name=TTYH2 {ECO:0000313|RefSeq:XP_028354777.2};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_028354777.2};
RN [1] {ECO:0000313|RefSeq:XP_028354777.2}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_028354777.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Probable chloride channel. {ECO:0000256|RuleBase:RU361114}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the tweety family.
CC {ECO:0000256|ARBA:ARBA00009849, ECO:0000256|RuleBase:RU361114}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU361114}.
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DR RefSeq; XP_028354777.2; XM_028498976.2.
DR AlphaFoldDB; A0A455C1E5; -.
DR KEGG; pcad:102984606; -.
DR Proteomes; UP000248484; Chromosome 14.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005254; F:chloride channel activity; IEA:UniProtKB-UniRule.
DR InterPro; IPR006990; Tweety.
DR PANTHER; PTHR12424:SF6; PROTEIN TWEETY HOMOLOG 2; 1.
DR PANTHER; PTHR12424; TWEETY-RELATED; 1.
DR Pfam; PF04906; Tweety; 1.
PE 3: Inferred from homology;
KW Chloride {ECO:0000256|RuleBase:RU361114};
KW Chloride channel {ECO:0000256|RuleBase:RU361114};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|RuleBase:RU361114};
KW Ion transport {ECO:0000256|RuleBase:RU361114};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361114};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361114};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361114};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361114}.
FT TRANSMEM 68..93
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361114"
SQ SEQUENCE 210 AA; 23196 MW; 3276F98F6F787F13 CRC64;
MQIQVTGLLQ FAVPLFPTAE KDLLRIQLLL NSSESSLHQL MAMLDCRGLH KDYLDALTGI
CYDGLEGLLY LGLFSLLAAL AFSTMICMGP GAWKHFATRD RDYDDMDDDP FNPQARRIAA
HNPPRGQLRS FCSYSSGLGS QTSLQPPAQT ISNAPVSEYM NQAVLFGGNP RYENVPLIGR
GSPPPTIQAT LPDVRRDHQE LTLSARTRTD
//
