ID A0A455C651_PHYMC Unreviewed; 309 AA.
AC A0A455C651;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=ATP-dependent RNA helicase DHX8 {ECO:0000313|RefSeq:XP_028355362.1, ECO:0000313|RefSeq:XP_028355363.1};
GN Name=DHX8 {ECO:0000313|RefSeq:XP_028355362.1,
GN ECO:0000313|RefSeq:XP_028355363.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_028355363.1};
RN [1] {ECO:0000313|RefSeq:XP_028355362.1, ECO:0000313|RefSeq:XP_028355363.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_028355362.1,
RC ECO:0000313|RefSeq:XP_028355363.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_028355362.1; XM_028499561.2.
DR RefSeq; XP_028355363.1; XM_028499562.2.
DR STRING; 9755.ENSPCTP00005017211; -.
DR Ensembl; ENSPCTT00005018991; ENSPCTP00005017211; ENSPCTG00005012269.
DR KEGG; pcad:114487738; -.
DR OrthoDB; 5488182at2759; -.
DR Proteomes; UP000248484; Chromosome 14.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.20.120.1080; -; 1.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF85; ATP-DEPENDENT RNA HELICASE DHX8; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00847; HA2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022806,
KW ECO:0000313|RefSeq:XP_028355362.1};
KW Helicase {ECO:0000256|ARBA:ARBA00022806,
KW ECO:0000313|RefSeq:XP_028355362.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022806,
KW ECO:0000313|RefSeq:XP_028355362.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022806,
KW ECO:0000313|RefSeq:XP_028355362.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484}.
FT DOMAIN 45..135
FT /note="Helicase-associated"
FT /evidence="ECO:0000259|SMART:SM00847"
SQ SEQUENCE 309 AA; 35980 MW; 03125BE4F5BEEF24 CRC64;
MLTTNVPEIQ RTNLASTVLS LKAMGINDLL SFDFMDAPPM ETLITAMEQL YTLGALDDEG
LLTRLGRRMA EFPLEPMLCK MLIMSVHLGC SEEMLTIVSM LSVQNVFYRP KDKQALADQK
KAKFHQTEGD HLTLLAVYNS WKNNKFSNPW CYENFIQARS LRRAQDIRKQ MLGIMDRHKL
DVVSCGKSTV RVQKAICSGF FRNAAKKDPQ EGYRTLIDQQ VVYIHPSSAL FNRQPEWVVY
HELVLTTKEY MREVTTIDPR WLVEFAPAFF KVSDPTKLSK QKKQQRLEPL YNRYEEPNAW
RISRAFRRR
//
