ID A0A480F636_PIG Unreviewed; 907 AA.
AC A0A480F636; F1SND0;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 {ECO:0000313|Ensembl:ENSSSCP00000005851.4};
DE SubName: Full=Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 {ECO:0000313|EMBL:HCZ95499.1};
GN Name=SVEP1 {ECO:0000313|Ensembl:ENSSSCP00000005851.4,
GN ECO:0000313|VGNC:VGNC:93642};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|EMBL:HCZ95499.1};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000005851.4, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000005851.4,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:HCZ95499.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=30723633; DOI=.7717/peerj.6374;
RA Gilbert D.G.;
RT "Genes of the pig, Sus scrofa, reconstructed with EvidentialGene.";
RL PeerJ 7:E6374-E6374(2019).
RN [3] {ECO:0000313|Ensembl:ENSSSCP00000005851.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR EMBL; DQIR01040024; HCZ95499.1; -; Transcribed_RNA.
DR EMBL; DQIR01084407; HDA39883.1; -; Transcribed_RNA.
DR EMBL; DQIR01134802; HDA90278.1; -; Transcribed_RNA.
DR EMBL; DQIR01225095; HDB80572.1; -; Transcribed_RNA.
DR Ensembl; ENSSSCT00000006000.4; ENSSSCP00000005851.4; ENSSSCG00000005455.5.
DR VGNC; VGNC:93642; SVEP1.
DR eggNOG; KOG1217; Eukaryota.
DR eggNOG; KOG4297; Eukaryota.
DR GeneTree; ENSGT00940000156061; -.
DR HOGENOM; CLU_000343_0_0_1; -.
DR TreeFam; TF342247; -.
DR Proteomes; UP000008227; Chromosome 1.
DR Bgee; ENSSSCG00000005455; Expressed in stomach and 33 other cell types or tissues.
DR CDD; cd00033; CCP; 3.
DR CDD; cd01450; vWFA_subfamily_ECM; 1.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 3.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR003410; HYR_dom.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR InterPro; IPR011641; Tyr-kin_ephrin_A/B_rcpt-like.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR19325; COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR19325:SF43; SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF07699; Ephrin_rec_like; 1.
DR Pfam; PF02494; HYR; 2.
DR Pfam; PF00084; Sushi; 3.
DR Pfam; PF00092; VWA; 1.
DR SMART; SM00032; CCP; 4.
DR SMART; SM01411; Ephrin_rec_like; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 3.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50825; HYR; 2.
DR PROSITE; PS50923; SUSHI; 4.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..907
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041166490"
FT DOMAIN 85..266
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 378..437
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 438..497
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 498..563
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 562..644
FT /note="HYR"
FT /evidence="ECO:0000259|PROSITE:PS50825"
FT DOMAIN 645..726
FT /note="HYR"
FT /evidence="ECO:0000259|PROSITE:PS50825"
FT DOMAIN 727..791
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DISULFID 408..435
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 468..495
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 907 AA; 100470 MW; BCB6DFC233F27786 CRC64;
MWARLAFCCW GLALVSGWAT FQQLSPSRNF SFRLFPEAAP GAPGRLPALP TPGEDSAAAE
SKVERLGQAF RRRVRRLREL SERLELVFLV DESSSVGQAN FLSELKFVRK LLSDFPVVPT
ATRVAIVTFS SKNNVVPRVD YISSRRAHQH KCALLSREIP AITYRGGGTY TKGAFQQAAQ
ILRHSRENST KVIFLITDGY SNGGDPRPIA ASLRDFGVEI FTFGIWQGNI RELNDMASTP
KEEHCYLLHS FEEFEALARR ALHEDLPSGS FIQEDMSHCS YLCEAGQDCC DQMASCKCGT
HTGQFECICE KGYYGKGLQY ECTACPSGTY KPEGSPGGIS TCLPCPDENH TSPPGSTSPE
DCVCKEGYRA SGQTCEVVHC PALKPPENGY FIQNTCNNHF NAACGVRCHP GFDLVGSSIF
LCLPNGLWSG SESSCRVRTC PRLRQPKHGH LSCSMGEMSY RTVCLVTCDE GYRLEGSAKL
TCQVNGQWDG LEPRCVERHC STFQKPKGVI VSPPSCGKHL AKPGMICQLS CRQGFILSGV
REEVRCTPSG KWSAKIQTAA CKDVEAPQIS CPADIEAETQ EQQDSANITW QIPTAKDNSG
EKVSIHVYPA FTPPYLFPIG DVAITYTAVD LSSNQASCTF HIKVIDVEPP SIDRCRSPPP
IQVSEKEHPA TWDEPQFSDN SGAMLAVTRS HSPGDLFPHG ETVVRYTATD PSGNNRTCDI
HIVIKGSPCE VPFTPINGDF ICTQDNTGVN CTLSCLEGYD FTEGSTDKYY CAYEDGIWRP
PYSTEWPDCA IKRFANHGFK SFEMLYKATR CDDTDLLKKF SEAFETTLGK MVPSFCSDAD
DIDCRLEDLT KKYCLEYNYD YENGFAIGNY VTLCGWFAKL ICKLRKSFQN SSANEKNECY
SCMHQVF
//
