ID A0A482WQ66_LAOST Unreviewed; 2217 AA.
AC A0A482WQ66;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Afadin {ECO:0008006|Google:ProtNLM};
GN ORFNames=LSTR_LSTR005146 {ECO:0000313|EMBL:RZF35618.1};
OS Laodelphax striatellus (Small brown planthopper) (Delphax striatella).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Auchenorrhyncha; Fulgoroidea;
OC Delphacidae; Criomorphinae; Laodelphax.
OX NCBI_TaxID=195883 {ECO:0000313|EMBL:RZF35618.1, ECO:0000313|Proteomes:UP000291343};
RN [1] {ECO:0000313|EMBL:RZF35618.1, ECO:0000313|Proteomes:UP000291343}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lst14 {ECO:0000313|EMBL:RZF35618.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:RZF35618.1};
RX PubMed=29136191; DOI=.1093/gigascience/gix109;
RA Zhu J., Jiang F., Wang X., Yang P., Bao Y., Zhao W., Wang W., Lu H.,
RA Wang Q., Cui N., Li J., Chen X., Luo L., Yu J., Kang L., Cui F.;
RT "Genome sequence of the small brown planthopper, Laodelphax striatellus.";
RL Gigascience 6:1-12(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RZF35618.1}.
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DR EMBL; QKKF02028001; RZF35618.1; -; Genomic_DNA.
DR STRING; 195883.A0A482WQ66; -.
DR InParanoid; A0A482WQ66; -.
DR Proteomes; UP000291343; Unassembled WGS sequence.
DR GO; GO:0005911; C:cell-cell junction; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd22711; FHA_AFDN; 1.
DR CDD; cd15471; Myo5p-like_CBD_afadin; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd01782; RA1_Afadin; 1.
DR CDD; cd01781; RA2_Afadin; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR InterPro; IPR028842; Afadin.
DR InterPro; IPR037977; CBD_Afadin.
DR InterPro; IPR002710; Dilute_dom.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR10398; AFADIN; 1.
DR PANTHER; PTHR10398:SF2; AFADIN; 1.
DR Pfam; PF01843; DIL; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF00788; RA; 2.
DR SMART; SM01132; DIL; 1.
DR SMART; SM00240; FHA; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00314; RA; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 2.
DR PROSITE; PS51126; DILUTE; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50200; RA; 2.
PE 4: Predicted;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Reference proteome {ECO:0000313|Proteomes:UP000291343}.
FT DOMAIN 44..138
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT DOMAIN 237..348
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT DOMAIN 661..904
FT /note="Dilute"
FT /evidence="ECO:0000259|PROSITE:PS51126"
FT DOMAIN 1005..1090
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 158..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 492..588
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1202..1382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1404..1733
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1797..1864
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1885..1932
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1947..2091
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2103..2122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2187..2217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 492..509
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..584
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1202..1262
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1280..1382
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1404..1490
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1496..1514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1515..1536
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1545..1618
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1651..1665
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1693..1708
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1713..1733
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1797..1813
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1829..1852
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1895..1931
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2196..2217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2217 AA; 246813 MW; EB614C70EB6AC5A2 CRC64;
MNAEMALVVR RNEERDALRT VIQAWNANRL DLFELSEPND ELEFHGVMRF YFQDSGQKVA
TKCIRVASDA TAQVVIETLI EKFRPDMRML SIPEYALYEI HENGEERRLD NEEKPLLVQL
NWHKDDREGR FLLRRIDDKT NMPEGTFQEA GSSFRRKLSK REKKQLKKQE KLNRMKSTGG
INDENDSGVA EKLYTELPET SFTRSISNPE AVMRRRRQQI LERKLQQFRS KDGGPDTGGT
LKIYGESLCR DVPYKTLLLS VRDSATQVVK EMLNKYGLDR EDPHNYCLVQ VNTAIEATEN
KDPSPGSNTN TINNREYILD EDECPLAILM NHPQSRGSIM FHVRRRPADY HPRKRKKKPQ
QKWNQQVDLD HRYDSLDRLP YFLELNPDGS EVAGAPRRHR LQPNVTEVGS ERASPHSQSQ
SLQLFGPNVQ PRHCVVAHTE GIVTVTPCSR DAETYVNGQR IYETTILQSG MIVQFGRIHS
FRFLDPCQED RRLRQDTSRP LHDYSYDRQS TQEESSPGPG AQSANQDAAS VTSPGSATVN
YETTFDVDGN IETRSTSSQG NRDDTRSQRS VGSSRDSNRL SNYDRYPRGT DPILPAVLEI
REETEEALLH ALVSDLEPNS PAFKLAPSYT LYLAARYRAS THYRPELTPT ERAHKLTLML
ARVAIMIHNT IQERYCEVKA LALWLANSSE LLHFLKSDRH ISAFSLDAQD TLADAVQIAF
RHLTGCLQRE LAAVMNNFLS ERDDIGHESE DPSTASVLGV MSSAMALLRR CRVNAALTIQ
LFSQLFHFVN VWAFNRVVAP NSTLCSRVWG LRIQARLAQI EAWAERQGLE LAADCHLARL
MQAAHLLQAP KYTADDLATL SSTCFKLNSL QLRALLQKYQ PSPDEPRLPH EMIENVVAEN
LADELARSDG REVRLEEDPE LALPFLLPED GYSCEVVRGV PQGLVEFIAP LQHAGLCRLT
AQPTSNGLWT VYMGPTNANM VRSPSAMSNR SGSCPVPQQE PEIQVIKLHK SNNGMGLSIV
AAKGAGQDRL GIYIKSVVKG GAADADGRLQ AGDQLLKVDG QSLVGITQEK AAEYLVRTGP
VVSLEVAKQG AIFHGLATLL SQPSPVMGRA NISAGVGSPG NHLHQLSSTS SSTTTCPNHP
IAFGRLAPSL SLGHLDRMQL SLAAEFNERS MDWSLRADVS AGPRRMSERD IPSRVLSENQ
LQLQQPMTTA NSQQQLMRPG QPYQPGQIQS SKSVPALHSG ASNEAGSNLA GPQQQQQQHV
GGGPGGGQGG PPRTPHEVFN PGYSRTSSTN SLPQKIEQPN AMRSRSSQNL LENRLPAPSS
NLGVRQVSNP SLHGQQQPQN HPPLYLPYQH QMSMQQQHQQ QIQQQMQQQQ QQQQPSAQIT
SPEGERFYQN LSVYRNQEIN NGYFVHQNSN SNHTGTPNTG RVKLPSPQDE RSPGMPNNGH
IMNNGNNNNN NNLMNNNNKS FKGSQSSLST SGRMSTEQMM NANNINRDRP SSAYLPPHSN
HLQQNMAPRS QSSRDMLRQE AKLQEMGEEV RRREARVTSP QQYPMHRMPA LQQQQQQQLQ
QQHHAQQQQM NNRPPMQQQH PQSPQQQQMM NNNMAYTSYG SPVTGQPYQA QPGAVLPGQQ
QHDYQARHPP IGGGKPMARP MADLQDGGSY SESPPPPPPP PTSTHPLYQR QDGPRYAASA
GEPPRGGYYP SSPSAGQGGQ QPPRAYQFQG TNPWEREERE KEALRRREAA RQWRDQQINE
LVALGTNRNS QQEEQLRALR LEREFQRRAA LEEDDDDEED QESAERVQGL LRVATTTGQF
PQTDDNGGNT VPSSGGGHLG GGTRRIPPST SRPPAQVNGI VGRTSMPPNA HTNNMPPAGP
GAEEKERLRR LKDLKMKQAE IESMKRREEE MRHQQQQQQQ QQQLQQQQHQ QQQGSNMRQQ
TVGSSPAAGN NMNHMKREMR LDNLIVNTPN GFASGSSPPQ QRLDSLLGQQ GSSPPQPPER
GSSFAIMSQS QLGSMRSPVS SSQSQNTLHN NNNTPTQQIV NNNNNNINAS QLTTPQTTNS
VGTAKRVSFQ DTTPTVVHSA NHTPSSTSSG TPSSNSNSMS TPSTLDNIRE DPNNFINEAE
SMLASPKSPD TPGYTGNTPG VIGAQEVYKD PRQRRLQEQH QKLMSNKVGT VPEKLSFKEK
MKMFAMETGE EGTPRDKVKI SRAQRDIDNL GTPIAGAANP GNSATNNGNG SSNGNNN
//
