ID A0A482X303_LAOST Unreviewed; 811 AA.
AC A0A482X303;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=HELP domain-containing protein {ECO:0000259|Pfam:PF03451};
GN ORFNames=LSTR_LSTR003421 {ECO:0000313|EMBL:RZF39760.1};
OS Laodelphax striatellus (Small brown planthopper) (Delphax striatella).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Auchenorrhyncha; Fulgoroidea;
OC Delphacidae; Criomorphinae; Laodelphax.
OX NCBI_TaxID=195883 {ECO:0000313|EMBL:RZF39760.1, ECO:0000313|Proteomes:UP000291343};
RN [1] {ECO:0000313|EMBL:RZF39760.1, ECO:0000313|Proteomes:UP000291343}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lst14 {ECO:0000313|EMBL:RZF39760.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:RZF39760.1};
RX PubMed=29136191; DOI=.1093/gigascience/gix109;
RA Zhu J., Jiang F., Wang X., Yang P., Bao Y., Zhao W., Wang W., Lu H.,
RA Wang Q., Cui N., Li J., Chen X., Luo L., Yu J., Kang L., Cui F.;
RT "Genome sequence of the small brown planthopper, Laodelphax striatellus.";
RL Gigascience 6:1-12(2017).
CC -!- SIMILARITY: Belongs to the WD repeat EMAP family.
CC {ECO:0000256|ARBA:ARBA00006489}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RZF39760.1}.
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DR EMBL; QKKF02019605; RZF39760.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A482X303; -.
DR STRING; 195883.A0A482X303; -.
DR InParanoid; A0A482X303; -.
DR Proteomes; UP000291343; Unassembled WGS sequence.
DR CDD; cd21931; TD_EMAP-like; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR049813; Elp-1-like_TD.
DR InterPro; IPR011048; Haem_d1_sf.
DR InterPro; IPR005108; HELP.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13720:SF50; ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 2; 1.
DR PANTHER; PTHR13720; WD-40 REPEAT PROTEIN; 1.
DR Pfam; PF03451; HELP; 1.
DR Pfam; PF00400; WD40; 5.
DR SMART; SM00320; WD40; 11.
DR SUPFAM; SSF51004; C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000291343};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 181..252
FT /note="HELP"
FT /evidence="ECO:0000259|Pfam:PF03451"
FT REPEAT 535..567
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 664..696
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 776..811
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 66..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 16..43
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 87..101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 811 AA; 89415 MW; B05B7EFF218D14E5 CRC64;
MESPGDTISG VINAWNDMIE TENESVRERV ADLEKKVLEQ GDEIVCLRST LADVLRRLNL
VEGARAVSHT PTTPTKNGGP GLLQLRPQQR ASPNNHHIGV NNHNGPPKDL RYRPLNEMAN
SKESIRRVAS YTPSSLPQRL ATNAKSLFNL HMRTNSQQNH TPMLKHGTRD ATYNSEDGSL
RMYLRGRPIV LYAPTPIAEG YEITKVATAP HSKLKLDWVY GYRGRDCRSN LYLLPTGEIV
YFVAAVVVLY NPEEQSQRHY LGHTDDVKCI AIHPNKLLVA SGQTAGHDTR EGRPHIRVWN
SVNLSTMAVI GIGEFERSIS CLSFSKADGG SLLCAVDEAN DHNISIWDWQ KGDKGHKITE
TKCSVDTVVA AEFHPLDKSC IVTCGKSHIS FWSLDNGGTL YKRNGIFENR DKPKYVTCLA
FTQTGDVLSG DSNGSIIVWG RGTNTITRFL RNVHEGSIFS ICVLKEGSII TGGGKDGRLI
QFDSELQKTG FEAQIAEHVG GVRTISEGRG SQLLVGSTRN CILVGSLPLG FSPAVLGHTD
ELWALAAHPN LSQFLTAGFD RIVQLWDCMA HSVVWSKDIA EQAQSAAFSP DGSIIIVGCV
SGKWLVMDAE TRELYSSHTD GSEPIQVVRY SPDGRFLALG SRDNNIYVYQ VGEDVRKYSR
VGRCAGHSSF ITHLDWSKNS EILRSNSGDY ELLFWNPSLC RQIPQSSSMR DMEWATHTCV
LSFSTVGICP EGADGTDVNA CERSHDENLI ATGDDFGKLN LYSYPACQPK SLNHTYGGHS
SHVTNVTFLH DDSRLISIGG KDTSVLQWSI I
//
