ID A0A482X991_LAOST Unreviewed; 1339 AA.
AC A0A482X991;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=DNA topoisomerase 2-binding protein 1-A {ECO:0008006|Google:ProtNLM};
GN ORFNames=LSTR_LSTR004381 {ECO:0000313|EMBL:RZF42232.1};
OS Laodelphax striatellus (Small brown planthopper) (Delphax striatella).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Auchenorrhyncha; Fulgoroidea;
OC Delphacidae; Criomorphinae; Laodelphax.
OX NCBI_TaxID=195883 {ECO:0000313|EMBL:RZF42232.1, ECO:0000313|Proteomes:UP000291343};
RN [1] {ECO:0000313|EMBL:RZF42232.1, ECO:0000313|Proteomes:UP000291343}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lst14 {ECO:0000313|EMBL:RZF42232.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:RZF42232.1};
RX PubMed=29136191; DOI=.1093/gigascience/gix109;
RA Zhu J., Jiang F., Wang X., Yang P., Bao Y., Zhao W., Wang W., Lu H.,
RA Wang Q., Cui N., Li J., Chen X., Luo L., Yu J., Kang L., Cui F.;
RT "Genome sequence of the small brown planthopper, Laodelphax striatellus.";
RL Gigascience 6:1-12(2017).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RZF42232.1}.
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DR EMBL; QKKF02015335; RZF42232.1; -; Genomic_DNA.
DR STRING; 195883.A0A482X991; -.
DR InParanoid; A0A482X991; -.
DR Proteomes; UP000291343; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProt.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR CDD; cd17731; BRCT_TopBP1_rpt2_like; 1.
DR CDD; cd17718; BRCT_TopBP1_rpt3; 1.
DR CDD; cd17738; BRCT_TopBP1_rpt7; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 8.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR PANTHER; PTHR13561; DNA REPLICATION REGULATOR DPB11-RELATED; 1.
DR PANTHER; PTHR13561:SF20; DNA TOPOISOMERASE 2-BINDING PROTEIN 1; 1.
DR Pfam; PF00533; BRCT; 5.
DR Pfam; PF12738; PTCB-BRCT; 1.
DR SMART; SM00292; BRCT; 6.
DR SUPFAM; SSF52113; BRCT domain; 6.
DR PROSITE; PS51379; 4FE4S_FER_2; 1.
DR PROSITE; PS50172; BRCT; 5.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000291343}.
FT DOMAIN 66..96
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 122..171
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 193..283
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 365..455
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 552..642
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 648..745
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 484..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 739..786
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 818..934
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 977..1040
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 740..773
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 821..898
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 979..1012
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1339 AA; 148927 MW; B66A5C78CFC7A1B7 CRC64;
MFPAKEVSIH FLVPGENEDD LSDEIKKTFQ DCKEARLKPQ LITEAALKEL DKSNKVIVVE
KFEGQLFEYL KRQKCIVCGP KCIQFCLAEK IPIPDTKSPV FITAMRDLVV SASNIPIPLK
CKVREKILHM GGKYTSNLVE SVTHLVTGGV QSKKYQKAAE KGISIMTVEW VDAVWNEGIR
RNVHATNSQF NKYKCPVFLD LYVTVSNMPQ SDKEKIKRLI NSNGGTYSKE MKKNETCLLI
IANVKNSQKF TFAQEWELPC VSPSWVYESV EKGYALPVDD YIMKPTVHNS TPTKDDIGRL
SFGAADISVV PGSTLSNQSV ASVMSNDTTL QLNRLSQKNA AKSKLSGNNS YKTYIDKLNV
GEAKRAGAFL EGCKVYLSGF KAEEQDKLRR ILTLGGAIVF VEISDAVSHV ICGEFVAADM
KAVNQSANRP FLVTVEWLVA SVNQQTAAPE EIYCHSIEVS SEPPEPPSPL SQKGLKLLKR
NETLSPDQTK LAPKEKSPDN STPKESHQSI VNRKLFGDCR TDQPAEDVND QPDAVIEIKD
GEENDAEEII TTEGPILKGL AFLILDFDDS NMEIIKTMIN EHGGKVVSQI FKGVTDQFTD
YTIVPIDWTP GQLKLQSTVV THFWLEDCIQ EEKLVPVMYY HEPLSILDGC APLAGCVITI
STYANKERAF LEQLVEALGA ISQEMFARKD NVAKGVKTCT HLITPSAGSQ KYMAALKWNI
PVVTKDWLLA CARTGTRLPE APHTVSSDGQ NPVSQTPTAC RAQGTNNSSN DGHVKDTPRP
KDEKRISIVP DFASKLTSQA DLQQKTCVAS HFEPVNEETP KRCVNTGNES QAITERSETP
AASSSTRSHQ TPSNSSISNK SKQSPQCTTD NPVQITRDAA SPSTSFQTPK NFDNKTRKSL
GLTPGYKFPS EMKTPDTPYE NIYPHSGAGK QARKRIKHCI DQFSQNAPNN PSPKKRKLST
PLSVLMKRAF DKFGLTPETS MLETDNTTGS DDINNDAETG NDKSFKTSTI GSRNDNADDE
PETSNKSETT KTPGKAPSGS EFLDVLNEKL QNLTPACQEV KRWIPDTTDQ IVSSRKSNES
KAQAQKACAS WDCEAQPIDV GWQEPVEERE KARELGMSKT RKFAFSNVNN EMKGKYEDMI
VSLGAALIKT DTYSSEITHL IIEGPKRSEK LLCSIAAGHY ILHTSYLDES HKCGYFLPED
QFEWGNELAK ENLPNLPVES ERLLADAAYR WRMKISNSKN KTGAYVKIKA IIFTNSNKMY
ENLFRLINSG NGEVLGRKED LNATHCFIDP KYNGKVNVQL LASKNIYCLN PVNLVNILVD
MQPKYETLIC EEYKKYYNF
//
