ID   A0A482XD44_LAOST        Unreviewed;       905 AA.
AC   A0A482XD44;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=protein-tyrosine-phosphatase {ECO:0000256|ARBA:ARBA00013064};
DE            EC=3.1.3.48 {ECO:0000256|ARBA:ARBA00013064};
GN   ORFNames=LSTR_LSTR001669 {ECO:0000313|EMBL:RZF43408.1};
OS   Laodelphax striatellus (Small brown planthopper) (Delphax striatella).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Paraneoptera; Hemiptera; Auchenorrhyncha; Fulgoroidea;
OC   Delphacidae; Criomorphinae; Laodelphax.
OX   NCBI_TaxID=195883 {ECO:0000313|EMBL:RZF43408.1, ECO:0000313|Proteomes:UP000291343};
RN   [1] {ECO:0000313|EMBL:RZF43408.1, ECO:0000313|Proteomes:UP000291343}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lst14 {ECO:0000313|EMBL:RZF43408.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:RZF43408.1};
RX   PubMed=29136191; DOI=.1093/gigascience/gix109;
RA   Zhu J., Jiang F., Wang X., Yang P., Bao Y., Zhao W., Wang W., Lu H.,
RA   Wang Q., Cui N., Li J., Chen X., Luo L., Yu J., Kang L., Cui F.;
RT   "Genome sequence of the small brown planthopper, Laodelphax striatellus.";
RL   Gigascience 6:1-12(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RZF43408.1}.
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DR   EMBL; QKKF02012754; RZF43408.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A482XD44; -.
DR   STRING; 195883.A0A482XD44; -.
DR   InParanoid; A0A482XD44; -.
DR   Proteomes; UP000291343; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR   GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR   GO; GO:0048666; P:neuron development; IEA:UniProt.
DR   Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 2.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR000242; PTP_cat.
DR   InterPro; IPR016130; Tyr_Pase_AS.
DR   InterPro; IPR003595; Tyr_Pase_cat.
DR   InterPro; IPR000387; Tyr_Pase_dom.
DR   InterPro; IPR008356; Tyr_Pase_KIM-con.
DR   PANTHER; PTHR46198; PROTEIN-TYROSINE-PHOSPHATASE; 1.
DR   PANTHER; PTHR46198:SF4; PROTEIN-TYROSINE-PHOSPHATASE; 1.
DR   Pfam; PF00102; Y_phosphatase; 2.
DR   PRINTS; PR01778; KIMPTPASE.
DR   PRINTS; PR00700; PRTYPHPHTASE.
DR   SMART; SM00194; PTPc; 1.
DR   SMART; SM00404; PTPc_motif; 1.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 2.
DR   PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR   PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR   PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000291343};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        24..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        146..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          335..895
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50055"
FT   DOMAIN          823..886
FT                   /note="Tyrosine specific protein phosphatases"
FT                   /evidence="ECO:0000259|PROSITE:PS50056"
FT   REGION          171..200
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          605..624
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          653..682
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   905 AA;  98037 MW;  E014D72D9E1E160F CRC64;
     MLAAVTFGNM AETKLLSVRL PCKTVFGCGC ILFVAASLSI FEGCFGAAIL DRREIWEGGL
     EEWQRGGGRG AAHASRLLMG PRATLNRDED DAADRLLDGK RSTQQLHFDS YNGAAMGEGV
     FSRVLEEDRG RGPWLQESDE GSRWHLLLFA LVGGLGLSVL ILVWLKNQMS QNSQSSSTEK
     EELVGGGGGG SGEEGAGGAS GGQWICHPVI RPMTTESLPS TSSTAVKRQL SIGCRGILPE
     VMTGRHAEGE PIRIRAKGLL ERRGSSASLT IDLLHPSQEN LTVTPTRECT AEEYLLSVGN
     VLSRKQLRAC LKDVRSLHRE FWDLPLNHPE KLTVPGSGSK NRYRTIIPNE ATRVQLPETS
     SSGTDSLTGY INANYIKGPL PHTVNDFWLM VWQQRAPVIV MFTRLWEKSR SKCEPYFPTD
     LNSTAVHNGI SITVASIKVK DGYTVRRFDL TKGDECRHTI HFWFDSWPDH KTPANAHSLL
     CLAKEVEIAR FLPSLQRRNS PSAWSVTRAA DAEPPSAPVA TPGLPCNFLS PRSAQISPTN
     PELTDVSPPS LKEISPVLNF GRLEFKDDPD TEADALITVE QEDRTSPQAT ADEISSLITL
     MEKQTATKED TSPNKPGPSL QKPIEINQQR QFNEMTHDDD SPLGGKVRPI KFGSLPHDNP
     KYADIDPDNA RSKSVENPPT WIEPSKDFNL SAVQKDTFEN IPTDIFSFGN LDTFASEPSP
     SPYEKQLSSK SIEGGTCSRF RLPSASDSVA AAEASAAGHR LSVDSPGLAG APDMASVGGS
     SFGSPAFGEV APWLRAWSPG PAGAASPRSP SLSGVQWGSD VPRGPAPAAG PVVVHCSAGI
     GRTGCFIAIS IGINQLLGEN NVDVLGIVCR MRYDRGGMVQ TAEQYEFIHR ALALFERSLP
     DQSGE
//