ID A0A484AU90_DRONA Unreviewed; 928 AA.
AC A0A484AU90;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=AP complex subunit beta {ECO:0000256|PIRNR:PIRNR002291};
GN ORFNames=AWZ03_013615 {ECO:0000313|EMBL:TDG39964.1};
OS Drosophila navojoa (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7232 {ECO:0000313|EMBL:TDG39964.1, ECO:0000313|Proteomes:UP000295192};
RN [1] {ECO:0000313|EMBL:TDG39964.1, ECO:0000313|Proteomes:UP000295192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Navoj_Jal97 {ECO:0000313|EMBL:TDG39964.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:TDG39964.1};
RX PubMed=30423125; DOI=.1093/jhered/esy059;
RA Vanderlinde T., Dupim E.G., Nazario-Yepiz N.O., Carvalho A.B.;
RT "An Improved Genome Assembly for Drosophila navojoa, the Basal Species in
RT the mojavensis Cluster.";
RL J. Hered. 110:118-123(2019).
CC -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC {ECO:0000256|ARBA:ARBA00006613, ECO:0000256|PIRNR:PIRNR002291}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDG39964.1}.
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DR EMBL; LSRL02000731; TDG39964.1; -; Genomic_DNA.
DR RefSeq; XP_017963616.1; XM_018108127.1.
DR RefSeq; XP_017963617.1; XM_018108128.1.
DR AlphaFoldDB; A0A484AU90; -.
DR STRING; 7232.A0A484AU90; -.
DR GeneID; 108656164; -.
DR KEGG; dnv:108656164; -.
DR OMA; NPPEVQW; -.
DR OrthoDB; 648032at2759; -.
DR Proteomes; UP000295192; Unassembled WGS sequence.
DR GO; GO:0030131; C:clathrin adaptor complex; IEA:InterPro.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 2.60.40.1150; -; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.310.10; TATA-Binding Protein; 1.
DR InterPro; IPR026739; AP_beta.
DR InterPro; IPR016342; AP_complex_bsu_1_2_4.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015151; B-adaptin_app_sub_C.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR InterPro; IPR008152; Clathrin_a/b/g-adaptin_app_Ig.
DR InterPro; IPR013041; Clathrin_app_Ig-like_sf.
DR InterPro; IPR013037; Clathrin_b-adaptin_app_Ig-like.
DR InterPro; IPR009028; Coatomer/calthrin_app_sub_C.
DR InterPro; IPR012295; TBP_dom_sf.
DR PANTHER; PTHR11134; ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER; 1.
DR PANTHER; PTHR11134:SF3; AP COMPLEX SUBUNIT BETA; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF02883; Alpha_adaptinC2; 1.
DR Pfam; PF09066; B2-adapt-app_C; 1.
DR PIRSF; PIRSF002291; AP_complex_beta; 1.
DR SMART; SM00809; Alpha_adaptinC2; 1.
DR SMART; SM01020; B2-adapt-app_C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF49348; Clathrin adaptor appendage domain; 1.
DR SUPFAM; SSF55711; Subdomain of clathrin and coatomer appendage domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002291};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR002291};
KW Reference proteome {ECO:0000313|Proteomes:UP000295192};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR002291}.
FT DOMAIN 698..807
FT /note="Clathrin adaptor alpha/beta/gamma-adaptin appendage
FT Ig-like subdomain"
FT /evidence="ECO:0000259|SMART:SM00809"
FT DOMAIN 816..926
FT /note="Beta-adaptin appendage C-terminal subdomain"
FT /evidence="ECO:0000259|SMART:SM01020"
FT REGION 593..619
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 598..619
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 928 AA; 101890 MW; 6B7B768CB209FBBA CRC64;
MTDSKYFTTT KKGEIFELKS ELNNDKKEKK KEAVKKVIAS MTVGKDVSAL FPDVVNCMQT
DNLELKKLVY LYLMNYAKSQ PDMAIMAVNT FVKDCEDSNP LIRALAVRTM GCIRVDKITE
YLCEPLRKCL KDEDPYVRKT AAVCVAKLYD ISATMVEDQG FLDQLKDLLS DSNPMVVANA
VAALSEINEA SQSGQPLVEM NSVTINKLLT ALNECTEWGQ VFILDSLANY SPKDEREAQS
ICERITPRLA HANAAVVLSA VKVLMKLLEM LSSDSDFCAT LTKKLAPPLV TLLSSEPEVQ
YVALRNINLI VQKRPDILKH EMKVFFVKYN DPIYVKLEKL DIMIRLANQS NIAQVLSELK
EYATEVDVDF VRKAVRAIGR CAIKVEPSAE RCVSTLLDLI QTKVNYVVQE AIVVIKDIFR
KYPNKYESII STLCENLDTL DEPEARASMV WIIGEYAERI DNADELLDSF LEGFQDENAQ
VQLQLLTAVV KLFLKRPSDT QELVQHVLSL ATQDSDNPDL RDRGFIYWRL LSTDPAAAKE
VVLADKPLIS EETDLLEPTL LDELICHISS LASVYHKPPT AFVEGRGAGV RKSLPNRAAG
SGNANADQSG EPGQGSESMV IPNQESLIGD LLSMDINAPA MPAAPASTTS NVDLLGGGLD
ILLGGPPAPV DSVAPAGGAS SLLGDIFGLA GTSLSVGVQI PKVTWLPAEK GKGLEIQGTF
SRRNGEIYMD MTLTNKAMQP MTNFAIQLNK NSFGLVPASP LQAPPLPPNQ STEVSLALAT
SGPIQRMEPL NNLQVAVKNN IDIFYFACLV HGNVLFAEDG QLDKRVFLNT WKEIPAANEL
QYSLSGVIGT TDGIASKMTT NNIFTIAKRN VEGQDMLYQS LKLTNNIWVL LELKLQPGNP
DATLSLKSRS VEVANIIFAA YEAIIRSP
//
