ID A0A484AX01_DRONA Unreviewed; 1550 AA.
AC A0A484AX01;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=FERM and PDZ domain-containing protein 4 {ECO:0008006|Google:ProtNLM};
GN ORFNames=AWZ03_012655 {ECO:0000313|EMBL:TDG40923.1};
OS Drosophila navojoa (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7232 {ECO:0000313|EMBL:TDG40923.1, ECO:0000313|Proteomes:UP000295192};
RN [1] {ECO:0000313|EMBL:TDG40923.1, ECO:0000313|Proteomes:UP000295192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Navoj_Jal97 {ECO:0000313|EMBL:TDG40923.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:TDG40923.1};
RX PubMed=30423125; DOI=.1093/jhered/esy059;
RA Vanderlinde T., Dupim E.G., Nazario-Yepiz N.O., Carvalho A.B.;
RT "An Improved Genome Assembly for Drosophila navojoa, the Basal Species in
RT the mojavensis Cluster.";
RL J. Hered. 110:118-123(2019).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDG40923.1}.
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DR EMBL; LSRL02000451; TDG40923.1; -; Genomic_DNA.
DR RefSeq; XP_017954179.1; XM_018098690.1.
DR STRING; 7232.A0A484AX01; -.
DR OMA; NQREGME; -.
DR OrthoDB; 2878981at2759; -.
DR Proteomes; UP000295192; Unassembled WGS sequence.
DR GO; GO:0071944; C:cell periphery; IEA:UniProt.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0009887; P:animal organ morphogenesis; IEA:UniProt.
DR GO; GO:0030182; P:neuron differentiation; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd17088; FERM_F1_FRMPD1_like; 1.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd00201; WW; 2.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.20.70.10; -; 2.
DR Gene3D; 2.30.42.10; -; 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR46221; FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER; 1.
DR PANTHER; PTHR46221:SF3; FERM DOMAIN (PROTEIN4.1-EZRIN-RADIXIN-MOESIN) FAMILY; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF00788; RA; 1.
DR Pfam; PF00397; WW; 2.
DR SMART; SM00295; B41; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00456; WW; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR SUPFAM; SSF51045; WW domain; 2.
DR PROSITE; PS50057; FERM_3; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000295192}.
FT DOMAIN 165..198
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 204..237
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 249..326
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 385..698
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 83..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 883..905
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 931..963
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 979..1037
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1220..1260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1288..1373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 947..963
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 979..1028
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1235..1259
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1300..1318
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1321..1336
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1550 AA; 168769 MW; EE8905DB7E5C635C CRC64;
MMLLPSGRSN SDVYPLQNVN TTATPASSVG GSKPLLLTRT SSPQLTTLQT LNGGGSGCGA
NAHTALRTNS SATFAATVAQ EAAGSLPGTG TQATATTSTT ASTTTTTTAI SATATAATAT
PNVNAVHTGF GAGALYGPIL GPSHAGNAPI GNWGEIDRHL DAVQEKLKAG WTVHVAKDGR
LYYCNHLTQS SGWLPACEDW SKHEELSYGW ERAIDSKGRS YYINHLNKTT TYEAPECIRW
DEHPPEPRLV QLQRSASLGF GFVAGSERPV IVRFVTEGGP SIGKLQPGDQ ILAVNGEDVK
DAPRDHVIQL VRACETQVSL LVCQPMAHCV LPGRKSTLLS AGKRAKLRTR PSRVRFAESV
CVNGAPLFPP SAFSLGDICV PPMANVLKVF LENGQTKSFK YDATTTVQDV VSSLLDKLCL
CCGELFSLVL EHVKSLKRNK LTLLDPQESL ARIAARPGAH KLRCLFRITF VPISAAELAQ
RDLNALDYLY MQCCNDVNQE RFAPELQPEL ALRLAALHMH QHALANNFAP AKLTVKLVER
EFGLERFVPV SLFEGMKRKE LRRLISHFLK VNAEMTGSSK VLTQLQAKLH YLDIIASLPS
YGAKCFSTNQ REGMERVLLV SPRFGLSQIS SARNSVPQPI SAIEDFTHVV VHREDDITCS
VSIYMLGDRA VKFIMEDRDA CEFSLVLGGY YRLLTGNVLN VLREREPNEE DNAPAFLSQH
TVLPASWSYL LPFHNRAHSV NFLMTPPYHP MPQQAVLSQP QPVQQQQQQL NYATDLDLHS
VMATELLEEA AKDSGLSDSS GSNYCTESRT QLAVEAKNEQ VLRRVQELQK LVQCSEQYLS
EQEQEVQQVP MQQLMQLQQQ REQTQQQIGQ SVAMLEFDSD CDSLNSSKVS STEESNHVSQ
PSLKHSDSLT LLAETISHEL TGITQGLNAI PEPISASAPP TPATPKRKPS LCSTSSPRPQ
RKFNGFSQLL SDLQALGTDF SQSESDSESV ASPAQSPTTR RPQQLLQAGS KQQQQHQQLA
QRSSFGLHSP DGTHFGAETK DYNLREYLQQ LKEISNVPDT DVAARQLSEI YGFEVREDTF
IETDTDLIDL RAIPPPQTPD ELDSLSLLNA APPKGFEGKA EELDSFLQEM LVAPPTQKAT
PAKELTPEEI MSFIIPPPPN LEAQSDRSEE CLYSNSVQAK REFFQAVANG NNSSQQNNHK
DQAAHVIEYP TVERKSKFSC CPTSKKEEAA PLEEAAPLQP PPRTPTIEHT TPPPARPPKS
AELLQRYSPK KQVRPVGHQP VVSVPLRELC PPQLPPRSSP TASSEPATPQ TATPATSAVS
APKKPPLPPI ANRPRPANGT PTPASNTSPP IPATARLPNA HSNGGQPALP KKPQQLHGEK
LFIKNGHLID GEALLAKTDV AMAGLLIKLD QVAAQCSAAQ SAGGGTSIDE DKFQRARNEL
TEQTLALVTA SKFLVASMSD MTLVNLPDHL TSCLTAIRRI TELAQDMTRH TSAPLQTRNI
VLKVHDVASS FRELVGVQIG PIGAGQLALQ AECLANVLAT LLRSLRVFSP
//
