ID A0A484B039_DRONA Unreviewed; 990 AA.
AC A0A484B039;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:TDG41221.1};
GN ORFNames=AWZ03_012350 {ECO:0000313|EMBL:TDG41221.1};
OS Drosophila navojoa (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7232 {ECO:0000313|EMBL:TDG41221.1, ECO:0000313|Proteomes:UP000295192};
RN [1] {ECO:0000313|EMBL:TDG41221.1, ECO:0000313|Proteomes:UP000295192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Navoj_Jal97 {ECO:0000313|EMBL:TDG41221.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:TDG41221.1};
RX PubMed=30423125; DOI=.1093/jhered/esy059;
RA Vanderlinde T., Dupim E.G., Nazario-Yepiz N.O., Carvalho A.B.;
RT "An Improved Genome Assembly for Drosophila navojoa, the Basal Species in
RT the mojavensis Cluster.";
RL J. Hered. 110:118-123(2019).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDG41221.1}.
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DR EMBL; LSRL02000389; TDG41221.1; -; Genomic_DNA.
DR STRING; 7232.A0A484B039; -.
DR OMA; WIYQINR; -.
DR OrthoDB; 5474711at2759; -.
DR Proteomes; UP000295192; Unassembled WGS sequence.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR CDD; cd10810; GH38N_AMII_LAM_like; 1.
DR Gene3D; 2.60.40.1360; -; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR011682; Glyco_hydro_38_C.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR013780; Glyco_hydro_b.
DR PANTHER; PTHR11607; ALPHA-MANNOSIDASE; 1.
DR PANTHER; PTHR11607:SF3; LYSOSOMAL ALPHA-MANNOSIDASE; 1.
DR Pfam; PF07748; Glyco_hydro_38C; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000295192};
KW Signal {ECO:0000256|SAM:SignalP}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..990
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019766133"
FT DOMAIN 36..350
FT /note="Glycoside hydrolase family 38 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01074"
FT DOMAIN 588..802
FT /note="Glycosyl hydrolase family 38 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07748"
SQ SEQUENCE 990 AA; 112699 MW; 1DDD87AFD2A8F2C0 CRC64;
MRFVALLAAV LVISSGPAEA KCGYEACPAT KANMINVHLV PHSHDDVGWL KTVDQYYYGS
RNNIQHAGVQ YILDSVIVEL HKNPDRRFIQ VETAFFWKWW EEQSEFVKQM VKLLVNEGRL
EFTGGAWSMN DEAAVHYQSV IDQFSLGLKL LNDTFGSCAR PRIGWQIDPF GHSREMASIF
AQMGYNGEFF ARMDHAEKSK RLDDVAMEMI WQSSESLSDS DIFTGLLYRH YSAPPGFCFD
LLCSDEPIID SKSYDNNVKA RVDDFISYVK KMSNSFRATH IMVPMGDDFQ YEDAEINFKN
MDKLIKYVNA RQVEGSKVNV FYSTPSCYLY ELHRMQLTWP EKKLDFFPYS SDVHSYWTGY
FTSRPTQKRX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
XXXXXXXXRL LTDAMVDAQD NARAALRVLT NLSTGQFDSC LELNISVCAF TRESANNVVV
TLFNPLAHPS TQFVRVPVKQ QQYLVTDEKG RAVPSELVPV PWQVLALQHR PNDTQHELVF
KATVDKLANY YIRVLPGPKA LQRFERVHSI RQERNRIEPK AETDELVVQN SQIKLTFVKS
TGHLKTIEMN GVSENIEQNF AIYKGAMGNN GVAQNRSSGA YIFRPDGEAT ILSDKIAYTV
YDGAQVKEVH QHVNEWISQV IRLYEGVNRV EFEWLVGPIP IDDDNGKEIV TRFKSGLVSN
GVFYTDSNGR EMIRRELNKR EYFTPIMTES VSGNYYPVTA RIALEDSQKR LALLNDRAQG
GSSLADGQLE LMLHRRLLRD DAFGVGEALN ETQFGTGLIA RGKVYLILNE AESKPSVAER
LAQQEIHLPF WKFFSSSNTA SAVKPLSIPD FSDFPQSVNL LTLEPYSTSE FLVRFENFMD
HNEGHTVSFN VRHIFDALNG KGIRETTLDG NMDLADMKRF KFHHDGSKPS TVEYFSSTYE
PLWATATSDA SRFSVTLSPM QIRTFIINWQ
//
