ID A0A484B1Q6_DRONA Unreviewed; 959 AA.
AC A0A484B1Q6;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Potassium channel domain-containing protein {ECO:0000259|Pfam:PF07885};
GN ORFNames=AWZ03_011806 {ECO:0000313|EMBL:TDG41761.1};
OS Drosophila navojoa (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7232 {ECO:0000313|EMBL:TDG41761.1, ECO:0000313|Proteomes:UP000295192};
RN [1] {ECO:0000313|EMBL:TDG41761.1, ECO:0000313|Proteomes:UP000295192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Navoj_Jal97 {ECO:0000313|EMBL:TDG41761.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:TDG41761.1};
RX PubMed=30423125; DOI=.1093/jhered/esy059;
RA Vanderlinde T., Dupim E.G., Nazario-Yepiz N.O., Carvalho A.B.;
RT "An Improved Genome Assembly for Drosophila navojoa, the Basal Species in
RT the mojavensis Cluster.";
RL J. Hered. 110:118-123(2019).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666,
CC ECO:0000256|RuleBase:RU003857}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDG41761.1}.
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DR EMBL; LSRL02000312; TDG41761.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A484B1Q6; -.
DR STRING; 7232.A0A484B1Q6; -.
DR OMA; ISDYCGK; -.
DR OrthoDB; 5406587at2759; -.
DR Proteomes; UP000295192; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003:SF346; OPEN RECTIFIER POTASSIUM CHANNEL PROTEIN 1; 1.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PRINTS; PR01333; 2POREKCHANEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU003857};
KW Ion transport {ECO:0000256|RuleBase:RU003857};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000295192};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003857};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857}.
FT TRANSMEM 41..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 38..95
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 136..217
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT REGION 400..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 540..621
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 708..743
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 774..959
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..589
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 713..730
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 775..789
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 808..822
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 847..863
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 871..930
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 959 AA; 104724 MW; 80E1097CEB68944E CRC64;
MEQLEDKNAT TQNEVLERIT DYCGKPVTDY TKDDYEIPYT WTFYHAFFFS FTVCSTVGYG
NISPTTFAGR MIMIVYSVIG IPVNGILFAG LGEYFGRTFE AIYRRYKKYK MSSDDHYVPP
QLGLITTVFI ALVPGIALFL LLPAWVFTYF ESWPYSISLY YSYVTTSTIG FGDYVPTFGA
NQPREFGGWF VVYQIFVIVW FIFSLGYLVM IMTFITRGLQ SKKLAYLEQQ LSSNLKATQN
RIWTGVTKDV GYLRRLLNEL YILKVKPVYT DTEFAYTVPR SASCPELSMY RVEPAPIPSR
KRAFSVCAEL ASQDPTVMVH ANSDTEISKF DREKTFETAE AYRQTTDLLA KVVTALATVQ
PPPPEADDAA MYGGYHGFSD SQILASEWSF STLNELSAPR RPRGRACSDF NIEPPRRPLR
APHNHNEWTW SGDNQQIQEA FNSRYKSQLN GAASDPHVVH LEEPDNSDEQ LKKNGAVAGA
GRVKKFSMPD GLRKLFHRKR PSQDLERKLS VVSVPEGITS LPTRSPLDFY NNTVTASASQ
SYLRNGRGPP PPFESTTSLA SSNGNAGISN PAFHLDDSDQ ATFGSTGPYQ RKSAAGVAAG
RRRRESIYTQ NPALSARRGS MYTPTATATA LQMQRRGSGS AAMAAVAARR GSLFPATGGM
TSNATPRRSS IFSVTSDKDM DVLEQTTIAD LIRALEVVHT HAVLDEHQKE QQQAAAAGGS
SSSSKLTKKQ RKLGNAGLDP PQLPPILSLF AGDQTRTLQA TAANRLYARR STIVGTMSPG
GSSGLATRRP SGIHNLEPPP SYTEKPLPPS TSTPTGQSKF RRRFSVRPTA LQIPPGQAPP
PGASLSEEPS PLTSSQTALQ RRLSLRPSPL ARELSPTSPT GAAGNAGQDE PGTSTSRLLP
SSLMRPSTSS THSPLSRIVQ ISQAQRKSSM PEGFATRKPG AGSASGPGSG TGSGNAGEK
//
