ID   A0A484B6M1_DRONA        Unreviewed;       870 AA.
AC   A0A484B6M1;
DT   05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT   05-JUN-2019, sequence version 1.
DT   13-SEP-2023, entry version 15.
DE   RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN   ORFNames=AWZ03_009272 {ECO:0000313|EMBL:TDG44299.1};
OS   Drosophila navojoa (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila.
OX   NCBI_TaxID=7232 {ECO:0000313|EMBL:TDG44299.1, ECO:0000313|Proteomes:UP000295192};
RN   [1] {ECO:0000313|EMBL:TDG44299.1, ECO:0000313|Proteomes:UP000295192}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Navoj_Jal97 {ECO:0000313|EMBL:TDG44299.1};
RC   TISSUE=Whole organism {ECO:0000313|EMBL:TDG44299.1};
RX   PubMed=30423125; DOI=.1093/jhered/esy059;
RA   Vanderlinde T., Dupim E.G., Nazario-Yepiz N.O., Carvalho A.B.;
RT   "An Improved Genome Assembly for Drosophila navojoa, the Basal Species in
RT   the mojavensis Cluster.";
RL   J. Hered. 110:118-123(2019).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:TDG44299.1}.
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DR   EMBL; LSRL02000109; TDG44299.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A484B6M1; -.
DR   STRING; 7232.A0A484B6M1; -.
DR   OMA; TEVCDSN; -.
DR   OrthoDB; 4153116at2759; -.
DR   Proteomes; UP000295192; Unassembled WGS sequence.
DR   GO; GO:0072487; C:MSL complex; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR   GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR   CDD; cd13122; MSL2_CXC; 1.
DR   CDD; cd16522; RING-HC_MSL2; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR037922; MSL2.
DR   InterPro; IPR032049; Msl2-CXC.
DR   InterPro; IPR032043; Msl2_Znf-RING.
DR   InterPro; IPR033467; Tesmin/TSO1-like_CXC.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR16048:SF3; E3 UBIQUITIN-PROTEIN LIGASE MSL2; 1.
DR   PANTHER; PTHR16048; MSL2-RELATED; 1.
DR   Pfam; PF16682; MSL2-CXC; 1.
DR   Pfam; PF16685; zf-RING_10; 1.
DR   SMART; SM01114; CXC; 1.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000295192};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          42..83
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REGION          537..581
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          797..816
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        540..554
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   870 AA;  92682 MW;  7AF05BDFC0B4FA92 CRC64;
     MEAQRLYIQI TLLSLKSASN LSTRRIHEIN TGIGELRQLL SCAVCCKLLN DPYKPKGRRC
     GHHVCRLCLR GRKNLWPSCP QCKDCSDFRT YEENKTMALQ LLCYKTLCVH LRQSALYSEF
     FHLRPDIKTS INIERKPRIR LPNRSTQWFI EEGANYESMS ETFLLQPDLP FLANAPSSLP
     AETPPTTAAT TPELPYEQHM PNQLSITDIE LEAAATGEQA QYAHPLPMMT SGARMLTHTH
     IAPQPQQVLI PADEPMLPAG YIESPWSDQV DLSGAFTIPA DYVNSTSNYT TYVMPNGEVH
     MAPIGQVVQL SHQEQLSEQD QLSQQEQVSQ EEQLGEVAAV EPMETVEADE PIVASTSKAT
     AFKPVDTSGS IKRRRAQLLL DHMEDEELLP STKAVAPTST LTNLRNKKPT IISSVQVKPP
     TATGSPIRTV AAAPIATAPA PVAAAPIAAV PAPISAVPAS LATVPASLAA VPVPISAVPP
     SMAIVPAPIA TAPASVAAVP APIAAIPAPI AAVSAPISAP ASKVIVPAAP KPVPTTVAKA
     APKSASTTAP KSASKTAAKA AVKPVPKPPA KPVAKPVTKP VAKGTSKSAA AAPIATVTKA
     ALPVAASVEA KAPVATAKML TMPNTSTPKA TVHKPKPKDA RMSHICRCGT TSAPGKATCR
     NSRCTCYVAG KSCVDCKCIG CKNPHQDATD TSDDEDFNMD IETEVAPAEE PAEEPTSAST
     DMQSGFTLVP LDNLQQSQHP LVLMQNENGQ YQGFNIFNGS EPVDPATLGF QRVPLRSNDG
     NSSIPEFAYI MPSPTVEPTT ATTEPHPPPS PTMERPAKRF KSFRNRLDME RSVLRKSADM
     LVSAGNAAAG DGSMDGDKDE AILERIFSDL
//