ID A0A484BBV7_DRONA Unreviewed; 592 AA.
AC A0A484BBV7;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 03-MAY-2023, entry version 16.
DE RecName: Full=T-box domain-containing protein {ECO:0000259|PROSITE:PS50252};
GN ORFNames=AWZ03_007264 {ECO:0000313|EMBL:TDG46293.1};
OS Drosophila navojoa (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7232 {ECO:0000313|EMBL:TDG46293.1, ECO:0000313|Proteomes:UP000295192};
RN [1] {ECO:0000313|EMBL:TDG46293.1, ECO:0000313|Proteomes:UP000295192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Navoj_Jal97 {ECO:0000313|EMBL:TDG46293.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:TDG46293.1};
RX PubMed=30423125; DOI=.1093/jhered/esy059;
RA Vanderlinde T., Dupim E.G., Nazario-Yepiz N.O., Carvalho A.B.;
RT "An Improved Genome Assembly for Drosophila navojoa, the Basal Species in
RT the mojavensis Cluster.";
RL J. Hered. 110:118-123(2019).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDG46293.1}.
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DR EMBL; LSRL02000061; TDG46293.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A484BBV7; -.
DR STRING; 7232.A0A484BBV7; -.
DR OMA; HKSRNES; -.
DR OrthoDB; 5323209at2759; -.
DR Proteomes; UP000295192; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd20193; T-box_TBX20-like; 1.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267:SF129; LP04777P-RELATED; 1.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR Pfam; PF00907; T-box; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Reference proteome {ECO:0000313|Proteomes:UP000295192};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 196..387
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
FT REGION 14..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 104..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 518..592
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..164
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 536..550
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 557..592
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 592 AA; 64962 MW; 7E7196BFD099E662 CRC64;
MLVGSHPYLC NGALPPVAPT SNNNNNNNAA TATPTTTTTA GNKSAAGSAT DFSIAAIMAR
EDASSRESSV RSASPISVED EVDVDVVDCS DAEEPPAKAR RLNHHHNHHH SHHHHHNNNN
NNNNNNNNNN SVSHKSRNES QLNTSSTSSQ GRCSTPPQSP GTEDSEERLT PEPVQKTPKI
VGSCNCDDLK PVQCHLETKE LWDRFHELGT EMIITKTGRR MFPTVRVSFS GPLRQIQPAD
RYAVLLDIIP MDSKRYRYAY HRSAWLVAGK ADPAPPARLY SHPDSPFSCE ALRKQVISFE
KVKLTNNEMD KNGQIVLNSM HRYQPRIHLV RLSHGQSIPS NPKELQDLDH KTYVFSETVF
TAVTAYQNQL ITKLKIDSNP FAKGFRDSSR LTDFDRDPME ALLLEQQLRS PLRLFPDPLM
QQFAAQQGAA DPASMALFEK ARQHLQMFGG NSPYAQLMMP QMYQAAAAAP PPPGLGAFHM
FQQQWPQLTA GFLASANQQA AAAQAAAQAQ AQAQAAAAAA MAANRTPPPP PTASTPSSTS
SGSPSPDMRP RQYQRFSPYQ LPAQAQQQQQ QQQQQQQPPP TAGSPASRSP AH
//
