ID A0A484BFV8_DRONA Unreviewed; 602 AA.
AC A0A484BFV8;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Fe2OG dioxygenase domain-containing protein {ECO:0000259|PROSITE:PS51471};
GN ORFNames=AWZ03_005891 {ECO:0000313|EMBL:TDG47747.1};
OS Drosophila navojoa (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7232 {ECO:0000313|EMBL:TDG47747.1, ECO:0000313|Proteomes:UP000295192};
RN [1] {ECO:0000313|EMBL:TDG47747.1, ECO:0000313|Proteomes:UP000295192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Navoj_Jal97 {ECO:0000313|EMBL:TDG47747.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:TDG47747.1};
RX PubMed=30423125; DOI=.1093/jhered/esy059;
RA Vanderlinde T., Dupim E.G., Nazario-Yepiz N.O., Carvalho A.B.;
RT "An Improved Genome Assembly for Drosophila navojoa, the Basal Species in
RT the mojavensis Cluster.";
RL J. Hered. 110:118-123(2019).
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|ARBA:ARBA00001954};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDG47747.1}.
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DR EMBL; LSRL02000040; TDG47747.1; -; Genomic_DNA.
DR RefSeq; XP_017961315.1; XM_018105826.1.
DR AlphaFoldDB; A0A484BFV8; -.
DR STRING; 7232.A0A484BFV8; -.
DR GeneID; 108654484; -.
DR KEGG; dnv:108654484; -.
DR OMA; PWKTKDE; -.
DR OrthoDB; 5473013at2759; -.
DR Proteomes; UP000295192; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR GO; GO:0106335; F:tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0043412; P:macromolecule modification; IEA:UniProt.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProt.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 2.60.120.590; Alpha-ketoglutarate-dependent dioxygenase AlkB-like; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR027450; AlkB-like.
DR InterPro; IPR037151; AlkB-like_sf.
DR InterPro; IPR013216; Methyltransf_11.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR13069:SF21; ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8; 1.
DR PANTHER; PTHR13069; UNCHARACTERIZED; 1.
DR Pfam; PF13532; 2OG-FeII_Oxy_2; 1.
DR Pfam; PF08241; Methyltransf_11; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000295192};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 211..316
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
SQ SEQUENCE 602 AA; 67605 MW; F44955639C5BE3C2 CRC64;
MHIEQKTNKV KKAEKKQRRS LAIIKADCNV SQSNSPTLYL AILNVGLSNG LTEEALLAAA
AATGGQVSQV LMLPSKSYCF LMCTTLADAQ LVYNGMHNRA TIGQKGAVAY LSYVMELPQQ
REENGWQKPL PGGLVLLPDF VSEAEETALL EAIAVGDAST ADSLKHRQVK HFGYEFLYGS
NNVNPLQPLE QGIPAACDFM WQRLDLPAFE PPDQLTVNEY EPGQGIPPHV DTHSAFKDPI
LSLSLQSDVV MDFRRGDQLV HVLLPRRSLL VMSGESRYDW THGIRPKHID VVATPSGSLT
TQARSKRTSL TFRRLRRGPC DCQYPTLCDT QQTATPQEVC DKLATHASHL EQQNVHEVYD
KIANHFSDTR HTPWPQVAEF LNSFEPQSVL LDVGCGNGKY LGCNPQLLSI GCDRSLGLLG
VGNARGLSVF RCDCLQLPVR SSSIDGCISI AVIHHLASSE RRLTALRELC RVLRPGGKAL
VYVWAKDQRR NDKKSTYLRQ NTAVNKEHTT EQAQRQKLAR QLESMDQQLP VPLPVHTNRT
EFQQQDVYVP WKTKDEQRTT FLRYYHVFEE LELEKLVDQM EGVVIRKSYY DQGNHCVIFE
KS
//
