ID A0A484BSM0_DRONA Unreviewed; 1068 AA.
AC A0A484BSM0;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 13-SEP-2023, entry version 16.
DE RecName: Full=Venom dipeptidyl peptidase 4 {ECO:0008006|Google:ProtNLM};
GN ORFNames=AWZ03_002309 {ECO:0000313|EMBL:TDG51222.1};
OS Drosophila navojoa (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7232 {ECO:0000313|EMBL:TDG51222.1, ECO:0000313|Proteomes:UP000295192};
RN [1] {ECO:0000313|EMBL:TDG51222.1, ECO:0000313|Proteomes:UP000295192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Navoj_Jal97 {ECO:0000313|EMBL:TDG51222.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:TDG51222.1};
RX PubMed=30423125; DOI=.1093/jhered/esy059;
RA Vanderlinde T., Dupim E.G., Nazario-Yepiz N.O., Carvalho A.B.;
RT "An Improved Genome Assembly for Drosophila navojoa, the Basal Species in
RT the mojavensis Cluster.";
RL J. Hered. 110:118-123(2019).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDG51222.1}.
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DR EMBL; LSRL02000010; TDG51222.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A484BSM0; -.
DR STRING; 7232.A0A484BSM0; -.
DR OMA; MRTPQEN; -.
DR Proteomes; UP000295192; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR InterPro; IPR002469; Peptidase_S9B_N.
DR PANTHER; PTHR11731:SF192; IP17501P; 1.
DR PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR Pfam; PF00930; DPPIV_N; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000295192};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 298..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 396..766
FT /note="Dipeptidylpeptidase IV N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00930"
FT DOMAIN 856..1059
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
FT REGION 97..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 140..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..156
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..174
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1068 AA; 120154 MW; 5C619386EF30E122 CRC64;
MNTYTNTNTN REHFLLSTNN LYGYSSCSGR DEKYLPASAA TAQQQYFRYH KQQQQQQQQQ
QLLQQPQSCM RHIPQQQQQQ QQQQQLRQMQ WEQQQQLVNS SSEFDEFHWP SKQLQQPDAV
GTVAGAVGGG GGGGVGKIYI TPADIPPPPH PPHPHPHPHG SNSHSHHNGN KSRHHQHPQS
AMTTPHRTPP HRCKCEHPIE LLDYDFEDAA AAASTASALH AHRHQHPPYY YKPAATLNSA
GAYQLRRHSA KLNESMLGGM GGSSLDDDDL HSSGGFGGGI NRFKNLVYSK EKKRRVRIIL
CVAAGVIAIA LLATMLVFIL RSDDENGSSD KPKDNAINLE DVLSGQLYAK RFNGSWSNGN
SVIYRVNADI VELDTKTQVV TTLLSNAAHY VLFEKSADGQ LLLLAKNYKK NFRYSFLAEY
DIYNLTSNTF TPLTIRNEQV LLSMVQWAPV GNALIMNFNR NLYYKKSALD PEIAITSDEN
GIFLNGIPDW VYEEEVFSSN VATWFNPTGT QIAFIQFDDS PTHVINFPYY GDAGDLRFQY
PLHQEIPYPK AGSSNPRVVL FTADLERALE GKEFLTSMPV PSALNTETDY IVTVVSWLDN
DNVLSVWMNR VQNAAYVITF DGRSRKVLYS IESKTGWVDL YTAPFKNRNG SKLAFVLPHD
NYKHLQLLAT DVSNAKLEPL TSGKFVVDSI LHWDATHDVI FYTANTEEHP EQLHLYAIRA
LATRKQTPKC LTCKLMTSGD VEQSYYSAVF NDNNQTVISS LGPGIPTTAV YEWTYANSQV
TLKKLMDWEN NDVLRSKLRG VALPTHRILT VNIDGGFQAK VLLQLPPNLD TSGSTKYPML
VDVYGGPDSY SVTNKWMMDW GTYLSSNQSV IYAKIDGRGS GLRGENLLHA IYLQLGTVEI
SDQIKVTQNL TKMFDYIDDE HIGIWGWSYG GYAAAMALAN DDNGVFKCAA SIAPVTDWTY
YDSIYTERYM GLPETNEIGY ANSRLSTRAQ KLRGKKYLLV HGTSDDNVHY QQAMILAKNL
ERHDILFKQI SYADEDHGLV NVRPHLYHSL DRFFGECFAS SRLMKSAK
//
