ID A0A484BT92_DRONA Unreviewed; 110 AA.
AC A0A484BT92;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 13-SEP-2023, entry version 16.
DE RecName: Full=Mitochondrial pyruvate carrier {ECO:0000256|RuleBase:RU363100};
GN ORFNames=AWZ03_001677 {ECO:0000313|EMBL:TDG52007.1};
OS Drosophila navojoa (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7232 {ECO:0000313|EMBL:TDG52007.1, ECO:0000313|Proteomes:UP000295192};
RN [1] {ECO:0000313|EMBL:TDG52007.1, ECO:0000313|Proteomes:UP000295192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Navoj_Jal97 {ECO:0000313|EMBL:TDG52007.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:TDG52007.1};
RX PubMed=30423125; DOI=.1093/jhered/esy059;
RA Vanderlinde T., Dupim E.G., Nazario-Yepiz N.O., Carvalho A.B.;
RT "An Improved Genome Assembly for Drosophila navojoa, the Basal Species in
RT the mojavensis Cluster.";
RL J. Hered. 110:118-123(2019).
CC -!- FUNCTION: Mediates the uptake of pyruvate into mitochondria.
CC {ECO:0000256|RuleBase:RU363100}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004448,
CC ECO:0000256|RuleBase:RU363100}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004448, ECO:0000256|RuleBase:RU363100}.
CC -!- SIMILARITY: Belongs to the mitochondrial pyruvate carrier (MPC) (TC
CC 2.A.105) family. {ECO:0000256|ARBA:ARBA00006416,
CC ECO:0000256|RuleBase:RU363100}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDG52007.1}.
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DR EMBL; LSRL02000006; TDG52007.1; -; Genomic_DNA.
DR RefSeq; XP_017968653.1; XM_018113164.1.
DR AlphaFoldDB; A0A484BT92; -.
DR STRING; 7232.A0A484BT92; -.
DR GeneID; 108659969; -.
DR KEGG; dnv:108659969; -.
DR OMA; CTTHFWG; -.
DR OrthoDB; 3375631at2759; -.
DR Proteomes; UP000295192; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006850; P:mitochondrial pyruvate transmembrane transport; IEA:InterPro.
DR InterPro; IPR005336; MPC.
DR PANTHER; PTHR14154:SF3; MITOCHONDRIAL PYRUVATE CARRIER; 1.
DR PANTHER; PTHR14154; UPF0041 BRAIN PROTEIN 44-RELATED; 1.
DR Pfam; PF03650; MPC; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363100};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128,
KW ECO:0000256|RuleBase:RU363100};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792,
KW ECO:0000256|RuleBase:RU363100};
KW Reference proteome {ECO:0000313|Proteomes:UP000295192};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363100};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363100};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363100}.
FT TRANSMEM 21..43
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363100"
FT TRANSMEM 55..72
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363100"
SQ SEQUENCE 110 AA; 12405 MW; E3DFE21B7B9E5EF6 CRC64;
MSIRRAMSSS GSSSSAAEWR NYFLSTHFWG PVANWGIPIA AIADTSKHPK FISGRMTFAL
TLYSCIFMRF AYKVQPRNWL LFACHATNAS AQAFQGIRYL KYTYSNESSA
//
