ID A0A484BTI9_DRONA Unreviewed; 938 AA.
AC A0A484BTI9;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Nephrin {ECO:0008006|Google:ProtNLM};
GN ORFNames=AWZ03_002424 {ECO:0000313|EMBL:TDG51061.1};
OS Drosophila navojoa (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7232 {ECO:0000313|EMBL:TDG51061.1, ECO:0000313|Proteomes:UP000295192};
RN [1] {ECO:0000313|EMBL:TDG51061.1, ECO:0000313|Proteomes:UP000295192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Navoj_Jal97 {ECO:0000313|EMBL:TDG51061.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:TDG51061.1};
RX PubMed=30423125; DOI=.1093/jhered/esy059;
RA Vanderlinde T., Dupim E.G., Nazario-Yepiz N.O., Carvalho A.B.;
RT "An Improved Genome Assembly for Drosophila navojoa, the Basal Species in
RT the mojavensis Cluster.";
RL J. Hered. 110:118-123(2019).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDG51061.1}.
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DR EMBL; LSRL02000011; TDG51061.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A484BTI9; -.
DR STRING; 7232.A0A484BTI9; -.
DR OMA; MRGHHET; -.
DR Proteomes; UP000295192; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 6.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR23278; SIDESTEP PROTEIN; 1.
DR PANTHER; PTHR23278:SF30; SIDESTEP VIII, ISOFORM B; 1.
DR Pfam; PF08205; C2-set_2; 2.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000295192};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 636..658
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..116
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 121..219
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 229..323
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 328..420
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 425..517
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 523..616
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 664..689
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 665..689
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 938 AA; 102359 MW; CA0D12AB244DAB69 CRC64;
MSKLECPPVL SESIIGTMGR LPCNVTPPIY EDRVALVIWY KVGLKTPIYS VDTRDSNFAQ
GTHWSDETYR ERLSFHVEGR AGTLTIKSTA EEDTGEYRCR VDFQKSPTRN SKVNLTVITP
PESIIILDSK GATIKDHTLG PYNEGSSVNV TCVAIGGRPQ PRVTWWHGNT MFNSSGLGHP
LSERRVGNVL SLAKLKRKNL HMQLTCRAEN NNLTTPIISS IVLDMNLRPL IVKLQGENRP
LSAENSYQLS CVVIGSRPAP TITWWKGSTP MKNTHEIANP DGNMTTSVLT FTPTIDDRGK
FLSCRAEQSM IPESGMEDGW KLDIYHIPVV SLELGTNSLN ATLREGVDVF FECNIKSNPW
IYKVSWRHNG AILENNPAEG IVVANQSLVL QNASRARTGI YTCVGSNREG DGESNPVQLD
IRFAPVCRAG QRTTYSSGRH ETVKVACEID ANPAEATYVW KFNATQGETA DIPASLVAVD
RGRSVAHYTP MVENDYGTLL CWASNEIGDQ SEPCVYTIVP AGEPDPLLNC TLLNQTSSGF
QIECVEGFDG GLPQDFIMEV YMNGTTRYPK IYKSKKPYFE VSGLQPGMGY NVFLIAHNSK
GRSNATILQV YTLKDPEKQT DLSLANGPLI EDIRPFLGIL AGIVGSLFLV ALIIVVVVRV
HGSSGRDRNN YSHPGNGSSS TANGNGNLGI LGSNNNGSLG IGTLAHNGGQ SVQDMHRIGR
ETCHVTSSLD SIDKNPDIIP QDGHDVDDEW TTKGHNRAYA TAALAEQNAV ITSTTYDHIM
PTYAVVDKKT GPPTGHGQYI QYNTLIPVSK MGAYANQQQQ QQQQQQQQQQ QQQQQHQQKT
ELSYSELAGA PLVGNAVGVG GVQRLTPYCS ATLGRPRQTD LKRAEPNIYS QVNVMMDDEI
LADLQAATAS GSSYVAGAVV DNVGGTGGLY MQGYATRV
//
