ID A0A484BWL0_DRONA Unreviewed; 267 AA.
AC A0A484BWL0;
DT 05-JUN-2019, integrated into UniProtKB/TrEMBL.
DT 05-JUN-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};
GN ORFNames=AWZ03_000607 {ECO:0000313|EMBL:TDG53064.1};
OS Drosophila navojoa (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7232 {ECO:0000313|EMBL:TDG53064.1, ECO:0000313|Proteomes:UP000295192};
RN [1] {ECO:0000313|EMBL:TDG53064.1, ECO:0000313|Proteomes:UP000295192}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Navoj_Jal97 {ECO:0000313|EMBL:TDG53064.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:TDG53064.1};
RX PubMed=30423125; DOI=.1093/jhered/esy059;
RA Vanderlinde T., Dupim E.G., Nazario-Yepiz N.O., Carvalho A.B.;
RT "An Improved Genome Assembly for Drosophila navojoa, the Basal Species in
RT the mojavensis Cluster.";
RL J. Hered. 110:118-123(2019).
CC -!- SUBCELLULAR LOCATION: Lysosome membrane
CC {ECO:0000256|ARBA:ARBA00004155}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004155}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361218}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU361218}.
CC -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC {ECO:0000256|ARBA:ARBA00006840, ECO:0000256|RuleBase:RU361218}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDG53064.1}.
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DR EMBL; LSRL02000002; TDG53064.1; -; Genomic_DNA.
DR RefSeq; XP_017955069.1; XM_018099580.1.
DR RefSeq; XP_017955070.1; XM_018099581.1.
DR RefSeq; XP_017955071.1; XM_018099582.1.
DR RefSeq; XP_017955072.1; XM_018099583.1.
DR AlphaFoldDB; A0A484BWL0; -.
DR STRING; 7232.A0A484BWL0; -.
DR GeneID; 108650440; -.
DR KEGG; dnv:108650440; -.
DR OMA; FTQPQVI; -.
DR OrthoDB; 2966000at2759; -.
DR Proteomes; UP000295192; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd03156; uroplakin_I_like_LEL; 1.
DR Gene3D; 1.10.1450.10; Tetraspanin; 1.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR InterPro; IPR000301; Tetraspanin_animals.
DR InterPro; IPR018503; Tetraspanin_CS.
DR InterPro; IPR008952; Tetraspanin_EC2_sf.
DR PANTHER; PTHR19282; TETRASPANIN; 1.
DR PANTHER; PTHR19282:SF216; TETRASPANIN-1; 1.
DR Pfam; PF00335; Tetraspanin; 1.
DR PIRSF; PIRSF002419; Tetraspanin; 1.
DR PRINTS; PR00259; TMFOUR.
DR SUPFAM; SSF48652; Tetraspanin; 1.
DR PROSITE; PS00421; TM4_1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361218};
KW Reference proteome {ECO:0000313|Proteomes:UP000295192};
KW Transmembrane {ECO:0000256|RuleBase:RU361218};
KW Transmembrane helix {ECO:0000256|RuleBase:RU361218}.
FT TRANSMEM 12..37
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
FT TRANSMEM 66..87
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
FT TRANSMEM 99..120
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
FT TRANSMEM 234..256
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
SQ SEQUENCE 267 AA; 30184 MW; 25C1F49A4B7C1B62 CRC64;
MVFDCGVWCA KYLLCILNFI FFVLGTIIFG VGLWLAVDKH SLIALLKLVE SERIEHFTQT
QVIEQMAYVL LVIGAVMFFL SLLGYLGAMR ESRCLLSTYG TLLILLLVAE LVAGGLAIFY
KERVRSESKK FLQTTITTYT LGENMDASSL MWNQLMGNFG CCGVNDYRDF DESEAWKNTK
GNRTIPDACC RLKDVAQLVP RDEDCATNPS DSNSYYMKGC YEVFTEWLIR QRELIIGVIV
TGIAHLVLVI LAFALCKAFA KYDDMRL
//
